Difference between revisions of "PolC"

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=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:'''
+
* '''Locus tag:''' BSU16580
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P13267 P13267]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P13267 P13267]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU16580 BSU16580]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU16580]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.7.7.7 2.7.7.7]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.7.7.7 2.7.7.7]

Revision as of 09:52, 3 June 2009

  • Description: DNA polymerase III (alpha subunit)

Gene name polC
Synonyms mutI, dnaF, dnaP
Essential yes PubMed
Product DNA polymerase III (alpha subunit)
Function DNA replication
MW, pI 162 kDa, 5.135
Gene length, protein length 4311 bp, 1437 aa
Immediate neighbours proS, ylxS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PolC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU16580

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1) (according to Swiss-Prot)
  • Protein family: PolC subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed