Difference between revisions of "AdaB"

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=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:'''
+
* '''Locus tag:''' BSU01820
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P19220 P19220]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P19220 P19220]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU01820 BSU01820]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU01820]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.1.1.63 2.1.1.63]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.1.1.63 2.1.1.63]

Revision as of 09:12, 3 June 2009

  • Description: O6-methylguanine-DNA methyltransferase

Gene name adaB
Synonyms
Essential no
Product O6-methylguanine-DNA methyltransferase
Function adaptive response to alkylative DNA damage
MW, pI 19 kDa, 6.152
Gene length, protein length 537 bp, 179 aa
Immediate neighbours adaA, ndhF
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AdaB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU01820

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: DNA (containing 6-O-methylguanine) + protein L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine (according to Swiss-Prot)
  • Protein family: MGMT family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed