Difference between revisions of "NadC"

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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:'''  
+
* '''Catalyzed reaction/ biological activity:''' Nicotinate D-ribonucleotide + diphosphate + CO<sub>2</sub> = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate (according to Swiss-Prot)
  
 
* '''Protein family:''' nadC/modD family (according to Swiss-Prot)
 
* '''Protein family:''' nadC/modD family (according to Swiss-Prot)

Revision as of 11:18, 24 May 2009

  • Description: nicotinate-nucleotide diphosphorylase (carboxylating)

Gene name nadC
Synonyms yrxB
Essential no
Product nicotinate-nucleotide diphosphorylase (carboxylating)
Function NAD biosynthesis
MW, pI 31 kDa, 5.18
Gene length, protein length 867 bp, 289 aa
Immediate neighbours nadA, nadB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
NadC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Nicotinate D-ribonucleotide + diphosphate + CO2 = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate (according to Swiss-Prot)
  • Protein family: nadC/modD family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed