Difference between revisions of "IlvC"
| Line 80: | Line 80: | ||
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P37253 P37253] | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P37253 P37253] | ||
| − | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU28290] | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU28290 BSU28290] |
* '''E.C. number:''' [http://www.expasy.org/enzyme/1.1.1.86 1.1.1.86] | * '''E.C. number:''' [http://www.expasy.org/enzyme/1.1.1.86 1.1.1.86] | ||
Revision as of 23:08, 13 May 2009
- Description: ketol-acid reductoisomerase (2,3-dihydroxy-3-methylbutanoate, 2-acetolactate)
| Gene name | ilvC |
| Synonyms | |
| Essential | no |
| Product | ketol-acid reductoisomerase (2,3-dihydroxy-3-methylbutanoate, 2-acetolactate) |
| Function | biosynthesis of branched-chain amino acids |
| MW, pI | 37 kDa, 5.37 |
| Gene length, protein length | 1026 bp, 342 aa |
| Immediate neighbours | leuA, ilvH |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P37253
- KEGG entry: BSU28290
- E.C. number: 1.1.1.86
Additional information
Expression and regulation
- Regulation: repressed by casamino acids PubMed , expressed in the absence of branched-chain amino acids (BCAA), expression is stimulated in the presence of glucose PubMed, repressed by CodY PubMed
- Regulatory mechanism: CodY: transcription repression PubMed, glucose regulation: CcpA PubMed, repression by BCAA: tRNA-controlled RNA switch (T-box) that mediates termination/antitermination
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
