Difference between revisions of "CymR"
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yrvO]]'', ''[[yrvN]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yrvO]]'', ''[[yrvN]]'' | ||
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| − | |style="background:#FAF8CC;" align="center"|'''[http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB14694]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' |
| − | |||
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|colspan="2" | '''Genetic context''' <br/> [[Image:yrzC_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yrzC_context.gif]] | ||
Revision as of 23:24, 16 April 2009
- Description: pleiotropic regulator of sulphur metabolism
| Gene name | cymR |
| Synonyms | yrzC |
| Essential | no |
| Product | transcription repressor |
| Function | regulation of sulphur metabolism |
| MW, pI | 11 kDa, 9.879 |
| Gene length, protein length | 333 bp, 111 aa |
| Immediate neighbours | yrvO, yrvN |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: Rrf2 family of transcription regulators
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Effectors of protein activity:
- Interactions: CymR-CysK, the complex is formed in the presence of cysteine, and results in DNA binding and repression of genes of cysteine biosynthesis PubMed
- Localization:
Database entries
- Structure:
- Swiss prot entry:
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Tanous et al. (2008) The CymR regulator in complex with the enzyme CysK controls cysteine metabolism in Bacillus subtilis.J. Biol. Chem. 283: 35551-35560. PubMed
- Even S., Burguiere P., Auger S., Soutourina O., Danchin A., Martin-Verstraete I. (2006) Global control of cysteine metabolism by CymR in Bacillus subtilis. J. Bacteriol 188: 2184-2197 PubMed
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
