Pta

• Description: phosphotransacetylase
  
  

Gene name	pta
Synonyms	ipa-88d, ywfJ
Essential	no
Product	phosphotransacetylase
Function	overflow metabolism
MW, pI	34 kDa, 4.649
Gene length, protein length	969 bp, 323 aa
Immediate neighbours	cysL, ywfI
Gene sequence (+200bp)	Protein sequence
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylation on (Ser-123 OR Thr-128 OR Ser-129) PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry:

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation: expression activated by glucose (2.6 fold) (CcpA) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Blencke et al. (2003) Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways. Metab Eng. 5: 133-149 PubMed
2. Macek et al. (2007) The serine/ threonine/ tyrosine phosphoproteome of the model bacterium Bacillus subtilis. Mol. Cell. Proteomics 6: 697-707 PubMed
3. Presecan-Siedel E, Galinier A, Longin R, Deutscher J, Danchin A, Glaser P, Martin-Verstraete I (1999) The catabolite regulation of the pta gene as part of carbon flow pathways in Bacillus subtilis. J Bacteriol 181:6889-6897. PubMed
4. Shin BS, Choi SK, Park SH. 1999. Regulation of the Bacillus subtilis phosphotransacetylase gene. J. Biochem. 126:333-339. PubMed
5. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed