Difference between revisions of "Stusti 2018"

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(Riboswitch modeling: Mark Sinzger)
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== Riboswitch modeling: Mark Sinzger ==
 
== Riboswitch modeling: Mark Sinzger ==
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<pubmed>19381267 28591515 27378291</pubmed>
  
 
== Protein- or tRNA-controlled RNA switches ==
 
== Protein- or tRNA-controlled RNA switches ==

Revision as of 08:50, 16 July 2018

Contents

Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas

What makes RNA such a special molecule – specific chemical and structural features of RNA


RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair


Ribozymes (catalytically active RNAs) (Intro)


The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology


The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity


Protein independent ribozymes – about Hammerhead, Varkud satellite, hairpin ribozyme & Co


RNA-based second messengers


Riboregulation and virulence, targeting by antibiotics


Riboswitches


Riboswitch modeling: Mark Sinzger


Protein- or tRNA-controlled RNA switches


RNA thermometers

Johanna Roßmanith, Franz Narberhaus
Exploring the modular nature of riboswitches and RNA thermometers.
Nucleic Acids Res: 2016, 44(11);5410-23
[PubMed:27060146] [WorldCat.org] [DOI] (I p)

Satya Narayan, Mamta H Kombrabail, Sudipta Das, Himanshu Singh, Kandala V R Chary, Basuthkar J Rao, Guruswamy Krishnamoorthy
Site-specific fluorescence dynamics in an RNA 'thermometer' reveals the role of ribosome binding in its temperature-sensitive switch function.
Nucleic Acids Res: 2015, 43(1);493-503
[PubMed:25477380] [WorldCat.org] [DOI] (I p)


The RNA world and evolution


RNA modification


RNA degradation/processing


Regulation by non-coding RNA



RNA dependent DNA Polymerases - from telomerase to retroviruses


RNA dependent RNA Polymerases – the RNA replicase

Sangita Venkataraman, Burra V L S Prasad, Ramasamy Selvarajan
RNA Dependent RNA Polymerases: Insights from Structure, Function and Evolution.
Viruses: 2018, 10(2);
[PubMed:29439438] [WorldCat.org] [DOI] (I e)

Kenneth K S Ng, Jamie J Arnold, Craig E Cameron
Structure-function relationships among RNA-dependent RNA polymerases.
Curr Top Microbiol Immunol: 2008, 320;137-56
[PubMed:18268843] [WorldCat.org] [DOI] (P p)

E K O'Reilly, C C Kao
Analysis of RNA-dependent RNA polymerase structure and function as guided by known polymerase structures and computer predictions of secondary structure.
Virology: 1998, 252(2);287-303
[PubMed:9878607] [WorldCat.org] [DOI] (P p)


CRISPR/Cas: Science – the bacterial “immune” system


CRISPR/Cas: Application and groundbreaking perspectives


The mysterious function and role of 6S-RNA and pRNA in bacteria


Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer


Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA)


Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways