Difference between revisions of "Stusti 2018"

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==  What makes RNA such a special molecule – specific chemical and structural features of RNA ==
 
==  What makes RNA such a special molecule – specific chemical and structural features of RNA ==
<pubmed>  21930584
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<pubmed>  21930584</pubmed>
</pubmed>
 
  
 
== RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair ==
 
== RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair ==
<pubmed>  24219496 8156586 28979293     26109351
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<pubmed>  24219496 8156586 28979293 26109351</pubmed>
</pubmed>
 
  
== Ribozymes (catalytically active RNAs)(Intro)==
+
== Ribozymes (catalytically active RNAs) (Intro)==
<pubmed>     21930582  
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<pubmed> 21930582</pubmed>
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== The Ribosome - the role and function of ribosomal RNAs     and the central dogma of molecular biology ==
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== The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology ==
<pubmed>     18292779 21930591 25500179
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<pubmed> 18292779 21930591 25500179</pubmed>
</pubmed>
 
  
 
== The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity ==
 
== The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity ==
<pubmed> 24452469 26682498 25798239
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<pubmed> 24452469,26682498 25798239 </pubmed>
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== Protein independent ribozymes – about Hammerhead,  Varkud satellite,  hairpin ribozyme & Co ==
 
== Protein independent ribozymes – about Hammerhead,  Varkud satellite,  hairpin ribozyme & Co ==
<pubmed> 22454536,14730013 10554775 21930585 6297745</pubmed>
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<pubmed> 22454536 14730013 10554775 21930585 6297745</pubmed>
  
 
== RNA-based second messengers ==
 
== RNA-based second messengers ==
<pubmed>28420751    25616065 25682701    25869574 26280533</pubmed>
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<pubmed> 28420751    25616065 25682701    25869574 26280533</pubmed>
  
 
== Riboregulation and virulence, targeting by antibiotics ==
 
== Riboregulation and virulence, targeting by antibiotics ==
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== Protein- or tRNA-controlled RNA switches ==
 
== Protein- or tRNA-controlled RNA switches ==
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25583497</pubmed>
 
  
 
== RNA thermometers ==
 
== RNA thermometers ==
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== RNA dependent DNA Polymerases - from telomerase to retroviruses==
 
== RNA dependent DNA Polymerases - from telomerase to retroviruses==
<pubmed>      18972389 26830230     28141967
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<pubmed>      18972389 26830230     28141967 </pubmed>  
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== RNA dependent RNA Polymerases – the RNA replicase ==
 
== RNA dependent RNA Polymerases – the RNA replicase ==
<pubmed>          29439438     18268843 9878607
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<pubmed>          29439438     18268843 9878607 </pubmed>  
</pubmed>  
 
  
 
== CRISPR/Cas: Science – the bacterial “immune” system ==
 
== CRISPR/Cas: Science – the bacterial “immune” system ==
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<pubmed>      29358495      29169146 28375731</pubmed>
    28375731</pubmed>
 
  
 
== CRISPR/Cas: Application and groundbreaking  perspectives ==
 
== CRISPR/Cas: Application and groundbreaking  perspectives ==
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== The mysterious function and role of 6S-RNA and pRNA in bacteria ==
 
== The mysterious function and role of 6S-RNA and pRNA in bacteria ==
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<pubmed>    24786589 17383220 24742053 23457253</pubmed>  
</pubmed>  
 
  
 
== Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer ==
 
== Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer ==
<pubmed>     22016848 26186290     21957054 23166520 21930591
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<pubmed>   22016848 26186290 21957054 23166520 21930591</pubmed>  
</pubmed>  
 
  
 
== Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA) ==
 
== Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA) ==
<pubmed>         28533025 25561718 26883671
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<pubmed>       28533025 25561718 26883671 28485684 29182528 21925379</pubmed>
    28485684 29182528 21925379
 
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== Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways ==
 
== Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways ==
<pubmed>   17627883     19943183   
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<pubmed> 17627883 19943183  </pubmed>
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Revision as of 12:37, 22 June 2018

Contents

Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas

What makes RNA such a special molecule – specific chemical and structural features of RNA


RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair


Ribozymes (catalytically active RNAs) (Intro)


The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology


The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity


Protein independent ribozymes – about Hammerhead, Varkud satellite, hairpin ribozyme & Co


RNA-based second messengers


Riboregulation and virulence, targeting by antibiotics


Riboswitches


Protein- or tRNA-controlled RNA switches


RNA thermometers


The RNA world and evolution

Ádám Kun, Ádám Radványi
The evolution of the genetic code: Impasses and challenges.
Biosystems: 2018, 164;217-225
[PubMed:29031737] [WorldCat.org] [DOI] (I p)

Thomas Fouqueau, Fabian Blombach, Finn Werner
Evolutionary Origins of Two-Barrel RNA Polymerases and Site-Specific Transcription Initiation.
Annu Rev Microbiol: 2017, 71;331-348
[PubMed:28657884] [WorldCat.org] [DOI] (I p)

Abe Pressman, Celia Blanco, Irene A Chen
The RNA World as a Model System to Study the Origin of Life.
Curr Biol: 2015, 25(19);R953-63
[PubMed:26439358] [WorldCat.org] [DOI] (I p)

Jessica C Bowman, Nicholas V Hud, Loren Dean Williams
The ribosome challenge to the RNA world.
J Mol Evol: 2015, 80(3-4);143-61
[PubMed:25739364] [WorldCat.org] [DOI] (I p)

Daniel Lundin, Gustav Berggren, Derek T Logan, Britt-Marie Sjöberg
The origin and evolution of ribonucleotide reduction.
Life (Basel): 2015, 5(1);604-36
[PubMed:25734234] [WorldCat.org] [DOI] (P e)

Paul G Higgs, Niles Lehman
The RNA World: molecular cooperation at the origins of life.
Nat Rev Genet: 2015, 16(1);7-17
[PubMed:25385129] [WorldCat.org] [DOI] (I p)

Markus Ralser
The RNA world and the origin of metabolic enzymes.
Biochem Soc Trans: 2014, 42(4);985-8
[PubMed:25109990] [WorldCat.org] [DOI] (I p)

Eugene V Koonin, Artem S Novozhilov
Origin and evolution of the genetic code: the universal enigma.
IUBMB Life: 2009, 61(2);99-111
[PubMed:19117371] [WorldCat.org] [DOI] (I p)

Yuri I Wolf, Eugene V Koonin
On the origin of the translation system and the genetic code in the RNA world by means of natural selection, exaptation, and subfunctionalization.
Biol Direct: 2007, 2;14
[PubMed:17540026] [WorldCat.org] [DOI] (I e)


RNA modification


RNA degradation/processing


Regulation by non-coding RNA



RNA dependent DNA Polymerases - from telomerase to retroviruses


RNA dependent RNA Polymerases – the RNA replicase


CRISPR/Cas: Science – the bacterial “immune” system


CRISPR/Cas: Application and groundbreaking perspectives


The mysterious function and role of 6S-RNA and pRNA in bacteria


Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer


Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA)


Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways