Difference between revisions of "Stusti 2018"
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= Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas = | = Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas = | ||
| − | == | + | == What makes RNA such a special molecule – specific chemical and structural features of RNA == |
| − | <pubmed> | + | <pubmed> 21930584 |
| + | </pubmed> | ||
| − | + | == RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair == | |
| − | + | <pubmed> 24219496 8156586 28979293 26109351 | |
| + | </pubmed> | ||
| + | == Ribozymes (catalytically active RNAs)== | ||
| + | <pubmed> 21930582 | ||
| + | </pubmed> | ||
| + | === The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology === | ||
| + | <pubmed> 18292779 21930591 25500179 | ||
| + | </pubmed> | ||
| − | + | === The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity === | |
| − | + | <pubmed> 24452469 26682498 25798239 | |
| − | + | </pubmed> | |
| − | + | === Protein independent ribozymes – about Hammerhead, Varkud satellite, hairpin ribozyme and Co. === | |
| + | <pubmed> 22454536 14730013 10554775 21930585 6297745 | ||
| + | </pubmed> | ||
| − | + | == RNA-based second messengers == | |
| − | + | <pubmed> 28420751 25616065 25682701 25869574 26280533</pubmed> | |
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== Riboregulation and virulence, targeting by antibiotics == | == Riboregulation and virulence, targeting by antibiotics == | ||
<pubmed>27651123 26416753 | <pubmed>27651123 26416753 | ||
| − | 27120414 | + | 27120414 27672192 28434876 28529506 28886688</pubmed> |
| − | + | == Riboswitches == | |
| − | + | <pubmed> 27607554 26655897 28121427 29618088 25794618 25794617 25848023 24769284 25571850 25964329 26118534 26494285 28206750 28375729 28396576 28541183 28455443 29537923 27798597 29135333 29420816 28611182</pubmed> | |
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== Protein- or tRNA-controlled RNA switches == | == Protein- or tRNA-controlled RNA switches == | ||
<pubmed>25959893 24816551 | <pubmed>25959893 24816551 | ||
| + | 25583497</pubmed> | ||
| − | |||
| − | |||
== RNA thermometers == | == RNA thermometers == | ||
| − | <pubmed>25477380</pubmed> | + | <pubmed>25477380 27060146 </pubmed> |
| − | + | ||
| − | |||
== The RNA world and evolution == | == The RNA world and evolution == | ||
| − | <pubmed> 25109990 | + | <pubmed> 25109990 25385129 25734234 25739364 26439358 17540026 29031737 28657884 19117371</pubmed> |
| − | + | == RNA modification == | |
| − | + | <pubmed> 26189113 26832457 27375676 | |
| + | 28264529 28624569</pubmed> | ||
| − | + | == RNA degradation/processing == | |
| − | + | <pubmed> 26096689 28202538 19239894 </pubmed> | |
| − | |||
| + | == Regulation by non-coding RNA == | ||
| + | <pubmed> 18981470 24667238 </pubmed> | ||
| − | == RNA | + | == RNAs as essential co-factors in protein enzymes == |
| − | <pubmed> | + | === RNA dependent DNA Polymerases - from telomerase to retroviruses=== |
| + | <pubmed> 18972389 26830230 28141967 | ||
| + | </pubmed> | ||
| − | + | === RNA dependent RNA Polymerases – the RNA replicase === | |
| + | <pubmed> 29439438 18268843 9878607 | ||
| + | </pubmed> | ||
| − | + | === CRISPR/Cas: Science – the bacterial “immune” system === | |
| + | <pubmed> 29358495 29169146 | ||
| + | 28375731</pubmed> | ||
| − | == | + | === CRISPR/Cas: Application and groundbreaking perspectives === |
| − | <pubmed> | + | <pubmed> 26771484 </pubmed> |
| − | == | + | === The mysterious function and role of 6S-RNA and pRNA in bacteria === |
| − | <pubmed> | + | <pubmed> 24786589 17383220 24742053 23457253 |
| + | </pubmed> | ||
| − | + | == Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer == | |
| + | <pubmed> 22016848 26186290 21957054 23166520 21930591 | ||
| + | </pubmed> | ||
| + | == Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA) == | ||
| + | <pubmed> 28533025 25561718 26883671 | ||
| + | 28485684 29182528 21925379 | ||
</pubmed> | </pubmed> | ||
| − | == | + | == Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways == |
| − | <pubmed> | + | <pubmed> 17627883 19943183 |
| − | + | </pubmed> | |
| − | |||
| − | |||
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Revision as of 12:28, 22 June 2018
Contents
- 1 Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas
- 1.1 What makes RNA such a special molecule – specific chemical and structural features of RNA
- 1.2 RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair
- 1.3 Ribozymes (catalytically active RNAs)
- 1.3.1 The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology
- 1.3.2 The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity
- 1.3.3 Protein independent ribozymes – about Hammerhead, Varkud satellite, hairpin ribozyme and Co.
- 1.4 RNA-based second messengers
- 1.5 Riboregulation and virulence, targeting by antibiotics
- 1.6 Riboswitches
- 1.7 Protein- or tRNA-controlled RNA switches
- 1.8 RNA thermometers
- 1.9 The RNA world and evolution
- 1.10 RNA modification
- 1.11 RNA degradation/processing
- 1.12 Regulation by non-coding RNA
- 1.13 RNAs as essential co-factors in protein enzymes
- 1.13.1 RNA dependent DNA Polymerases - from telomerase to retroviruses
- 1.13.2 RNA dependent RNA Polymerases – the RNA replicase
- 1.13.3 CRISPR/Cas: Science – the bacterial “immune” system
- 1.13.4 CRISPR/Cas: Application and groundbreaking perspectives
- 1.13.5 The mysterious function and role of 6S-RNA and pRNA in bacteria
- 1.14 Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer
- 1.15 Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA)
- 1.16 Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways
Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas
What makes RNA such a special molecule – specific chemical and structural features of RNA
RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair
Ribozymes (catalytically active RNAs)
The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology
The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity
Protein independent ribozymes – about Hammerhead, Varkud satellite, hairpin ribozyme and Co.
RNA-based second messengers
Jan Gundlach, Christina Herzberg, Volkhard Kaever, Katrin Gunka, Tamara Hoffmann, Martin Weiß, Johannes Gibhardt, Andrea Thürmer, Dietrich Hertel, Rolf Daniel, Erhard Bremer, Fabian M Commichau, Jörg Stülke
##Title##
Sci Signal: 2017, 10(475);
[PubMed:28420751]
[WorldCat.org]
[DOI]
(I e)
Christopher P Jones, Adrian R Ferré-D'Amaré
Recognition of the bacterial alarmone ZMP through long-distance association of two RNA subdomains.
Nat Struct Mol Biol: 2015, 22(9);679-85
[PubMed:26280533]
[WorldCat.org]
[DOI]
(I p)
Fabian M Commichau, Achim Dickmanns, Jan Gundlach, Ralf Ficner, Jörg Stülke
A jack of all trades: the multiple roles of the unique essential second messenger cyclic di-AMP.
Mol Microbiol: 2015, 97(2);189-204
[PubMed:25869574]
[WorldCat.org]
[DOI]
(I p)
Renée J St-Onge, Henry J Haiser, Mary R Yousef, Emma Sherwood, Natalia Tschowri, Mahmoud Al-Bassam, Marie A Elliot
Nucleotide second messenger-mediated regulation of a muralytic enzyme in Streptomyces.
Mol Microbiol: 2015, 96(4);779-95
[PubMed:25682701]
[WorldCat.org]
[DOI]
(I p)
Gregory S Ducker, Joshua D Rabinowitz
ZMP: a master regulator of one-carbon metabolism.
Mol Cell: 2015, 57(2);203-4
[PubMed:25616065]
[WorldCat.org]
[DOI]
(I p)
Riboregulation and virulence, targeting by antibiotics
Juan J Quereda, Pascale Cossart
Regulating Bacterial Virulence with RNA.
Annu Rev Microbiol: 2017, 71;263-280
[PubMed:28886688]
[WorldCat.org]
[DOI]
(I p)
Petra Dersch, Muna A Khan, Sabrina Mühlen, Boris Görke
Roles of Regulatory RNAs for Antibiotic Resistance in Bacteria and Their Potential Value as Novel Drug Targets.
Front Microbiol: 2017, 8;803
[PubMed:28529506]
[WorldCat.org]
[DOI]
(P e)
Hao Wang, Paul A Mann, Li Xiao, Charles Gill, Andrew M Galgoci, John A Howe, Artjohn Villafania, Christopher M Barbieri, Juliana C Malinverni, Xinwei Sher, Todd Mayhood, Megan D McCurry, Nicholas Murgolo, Amy Flattery, Matthias Mack, Terry Roemer
Dual-Targeting Small-Molecule Inhibitors of the Staphylococcus aureus FMN Riboswitch Disrupt Riboflavin Homeostasis in an Infectious Setting.
Cell Chem Biol: 2017, 24(5);576-588.e6
[PubMed:28434876]
[WorldCat.org]
[DOI]
(I p)
Andreas Matern, Danielle Pedrolli, Stephanie Großhennig, Jörgen Johansson, Matthias Mack
Uptake and Metabolism of Antibiotics Roseoflavin and 8-Demethyl-8-Aminoriboflavin in Riboflavin-Auxotrophic Listeria monocytogenes.
J Bacteriol: 2016, 198(23);3233-3243
[PubMed:27672192]
[WorldCat.org]
[DOI]
(I e)
Aaron M Nuss, Ann Kathrin Heroven, Petra Dersch
RNA Regulators: Formidable Modulators of Yersinia Virulence.
Trends Microbiol: 2017, 25(1);19-34
[PubMed:27651123]
[WorldCat.org]
[DOI]
(I p)
Daniel Dar, Maya Shamir, J R Mellin, Mikael Koutero, Noam Stern-Ginossar, Pascale Cossart, Rotem Sorek
Term-seq reveals abundant ribo-regulation of antibiotics resistance in bacteria.
Science: 2016, 352(6282);aad9822
[PubMed:27120414]
[WorldCat.org]
[DOI]
(I p)
John A Howe, Hao Wang, Thierry O Fischmann, Carl J Balibar, Li Xiao, Andrew M Galgoci, Juliana C Malinverni, Todd Mayhood, Artjohn Villafania, Ali Nahvi, Nicholas Murgolo, Christopher M Barbieri, Paul A Mann, Donna Carr, Ellen Xia, Paul Zuck, Dan Riley, Ronald E Painter, Scott S Walker, Brad Sherborne, Reynalda de Jesus, Weidong Pan, Michael A Plotkin, Jin Wu, Diane Rindgen, John Cummings, Charles G Garlisi, Rumin Zhang, Payal R Sheth, Charles J Gill, Haifeng Tang, Terry Roemer
Selective small-molecule inhibition of an RNA structural element.
Nature: 2015, 526(7575);672-7
[PubMed:26416753]
[WorldCat.org]
[DOI]
(I p)
Riboswitches
Protein- or tRNA-controlled RNA switches
RNA thermometers
The RNA world and evolution
RNA modification
RNA degradation/processing
Regulation by non-coding RNA
Yvonne Göpel, Muna A Khan, Boris Görke
Ménage à trois: post-transcriptional control of the key enzyme for cell envelope synthesis by a base-pairing small RNA, an RNase adaptor protein, and a small RNA mimic.
RNA Biol: 2014, 11(5);433-42
[PubMed:24667238]
[WorldCat.org]
[DOI]
(I p)
Boris Görke, Jörg Vogel
Noncoding RNA control of the making and breaking of sugars.
Genes Dev: 2008, 22(21);2914-25
[PubMed:18981470]
[WorldCat.org]
[DOI]
(P p)
RNAs as essential co-factors in protein enzymes
RNA dependent DNA Polymerases - from telomerase to retroviruses
RNA dependent RNA Polymerases – the RNA replicase
CRISPR/Cas: Science – the bacterial “immune” system
CRISPR/Cas: Application and groundbreaking perspectives
The mysterious function and role of 6S-RNA and pRNA in bacteria
Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer
Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA)
Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways
