Difference between revisions of "Apt"
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 510 bp, 170 aa | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 510 bp, 170 aa | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[relA]]'', ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[relA]]'', ''[[recJ]]'' |
|- | |- | ||
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27610 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27610 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27610 DNA_with_flanks] | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27610 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27610 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27610 DNA_with_flanks] | ||
| Line 37: | Line 37: | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
| − | + | <br/><br/> | |
| − | |||
| − | |||
| − | |||
| − | |||
= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
Revision as of 08:48, 7 July 2015
- Description: adenine phosphoribosyltransferase, universally conserved protein
| Gene name | apt |
| Synonyms | |
| Essential | no |
| Product | adenine phosphoribosyltransferase |
| Function | purine salvage and interconversion |
| Gene expression levels in SubtiExpress: apt | |
| Metabolic function and regulation of this protein in SubtiPathways: apt | |
| MW, pI | 18 kDa, 4.701 |
| Gene length, protein length | 510 bp, 170 aa |
| Immediate neighbours | relA, recJ |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides, universally conserved proteins, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU27610
Phenotypes of a mutant
Database entries
- BsubCyc: BSU27610
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate (according to Swiss-Prot)
- Protein family: purine/pyrimidine phosphoribosyltransferase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- phosphorylated on Arg-85 PubMed
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU27610
- Structure: 2DY0 (from Escherichia coli k12, 56% identity, 66% similarity)
- UniProt: O34443
- KEGG entry: [3]
- E.C. number: 2.4.2.7
Additional information
Expression and regulation
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
- number of protein molecules per cell (minimal medium with glucose and ammonium, exponential phase): 1738 PubMed
- number of protein molecules per cell (minimal medium with glucose and ammonium, early stationary phase after glucose exhaustion): 1189 PubMed
- number of protein molecules per cell (minimal medium with glucose and ammonium, late stationary phase after glucose exhaustion): 1706 PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
