Difference between revisions of "HtrC"
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* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
** [[HtrC]] is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of [[SubtInteract|interactions]] {{PubMed|21630458}} | ** [[HtrC]] is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of [[SubtInteract|interactions]] {{PubMed|21630458}} | ||
+ | ** [[HtrC]]-[[YpeB]], for proteolysis of [[YpeB]] during [[germination]] {{PubMed|25384476}} | ||
* '''[[Localization]]:''' cell membrane (according to Swiss-Prot) | * '''[[Localization]]:''' cell membrane (according to Swiss-Prot) |
Revision as of 15:38, 14 November 2014
- Description: similar to quality control membrane serine protease HtrA
Gene name | htrC |
Synonyms | yycK, yyxA |
Essential | no |
Product | putative quality control membrane protease |
Function | unknown |
Gene expression levels in SubtiExpress: htrC | |
MW, pI | 42 kDa, 5.315 |
Gene length, protein length | 1200 bp, 400 aa |
Immediate neighbours | yyzO, walJ |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
proteolysis, sporulation proteins, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU40360
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: peptidase S1B family (according to Swiss-Prot)
- Paralogous protein(s): HtrA
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
- Interactions:
- HtrC is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of interactions PubMed
- HtrC-YpeB, for proteolysis of YpeB during germination PubMed
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P39668
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor: for htrC: SigG PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Tim Clausen, Markus Kaiser, Robert Huber, Michael Ehrmann
HTRA proteases: regulated proteolysis in protein quality control.
Nat Rev Mol Cell Biol: 2011, 12(3);152-62
[PubMed:21326199]
[WorldCat.org]
[DOI]
(I p)
Original publications