Difference between revisions of "HtrC"

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(References)
(Extended information on the protein)
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* '''[[SubtInteract|Interactions]]:'''  
 
* '''[[SubtInteract|Interactions]]:'''  
 
** [[HtrC]] is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of [[SubtInteract|interactions]] {{PubMed|21630458}}
 
** [[HtrC]] is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of [[SubtInteract|interactions]] {{PubMed|21630458}}
 +
** [[HtrC]]-[[YpeB]], for proteolysis of [[YpeB]] during [[germination]] {{PubMed|25384476}}
  
 
* '''[[Localization]]:''' cell membrane (according to Swiss-Prot)
 
* '''[[Localization]]:''' cell membrane (according to Swiss-Prot)

Revision as of 15:38, 14 November 2014

  • Description: similar to quality control membrane serine protease HtrA

Gene name htrC
Synonyms yycK, yyxA
Essential no
Product putative quality control membrane protease
Function unknown
Gene expression levels in SubtiExpress: htrC
MW, pI 42 kDa, 5.315
Gene length, protein length 1200 bp, 400 aa
Immediate neighbours yyzO, walJ
Sequences Protein DNA DNA_with_flanks
Genetic context
YyxA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YyxA expression.png















Categories containing this gene/protein

proteolysis, sporulation proteins, membrane proteins

This gene is a member of the following regulons

SigG regulon

The gene

Basic information

  • Locus tag: BSU40360

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase S1B family (according to Swiss-Prot)
  • Paralogous protein(s): HtrA

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Tim Clausen, Markus Kaiser, Robert Huber, Michael Ehrmann
HTRA proteases: regulated proteolysis in protein quality control.
Nat Rev Mol Cell Biol: 2011, 12(3);152-62
[PubMed:21326199] [WorldCat.org] [DOI] (I p)

Original publications