Difference between revisions of "Main Page"

Revision as of 08:46, 5 August 2014

Welcome to SubtiWiki! - Bacillus subtilis annotation the "wiki" way!

Contact: General Microbiology, University of Göttingen, send mail

Upcoming events:

New: Subtiwiki is now on Facebook - please give it a +1!

Now online: A new description of SubtiWiki and its acompanying modules in the 2014 Database issue of Nucleic Acids Research

Paper of the month: August 2014

Calcium is important for the activity of many many enzymes, and its cellular homeostasis is therefore important. Now, the previously unknown YetJ protein has been identified as a pH-sensitive calcium leak that allows reducing the inracellular calcium concentration. Chang et al. report the structure of YetJ and explain how two conserved Asp residues sense changes in the pH.
Relevant SubtiWiki pages: Metal ion homeostasis (K, Na, Ca, Mg), YetJ

New procedure for account creation:

Due to massive spam attacks, we had to change our policy for the creation of accounts. If you want to create an account, just send me a mail. We will create the account for you as quickly as possible, then you can change your password. This does not affect existing accounts, which remain active.
Please remember that all members of the Bacillus community are invited to create accounts and to contribute to SubtiWiki!

News in SubtiWiki:

April 2013: SubtiWiki uses a new, faster Mediawiki platform! The times for page access are significantly reduced. Enjoy!
March 2013: updated Excel files that map all genes to categories and regulons as well as the general updated identity mapping of all genes were uploaded.
October 2012: the essential genes have been categorized
September 2012: 300 mutant strains available at the BGSC were added to the corresponding gene pages
August 2012: SubtiExpress, the new compagnon of SubtiWiki devoted to gene expression is online! Try it out!
April 2012: Links for expression data under 104 different conditions (based on Nicolas et al., 2012) have been added to the expression section of the individual gene pages
April 2011: SubtInteract, a presentation of protein-protein interactions in B. subtilis, is online!
December 2010: SubtiCellPublisher allows the conversion of CellDesigner diagrams to navigatable presentations in the style of SubtiPathways

Publications describing SubtiWiki and SubtiPathways:

@@ Line 21: / Line 21: @@
 <br/>
-<big>'''Paper of the month: July 2014'''</big>
+<big>'''Paper of the month: August 2014'''</big>
-* [[T-box]]es are regulatory mRNA elements which sense amino acid availability and control the expression of genes encoding aminoacyl-tRNA synthetases and biosynthetic enzymes. Sensing is thought to occur by the interaction of the uncharged tRNA with the T-box thus preventing the formation of a [[transcription]] terminator. It has however, not been known whether this regulation involves proteins. Now, [http://www.ncbi.nlm.nih.gov/pubmed/24954903 Zhang and Ferre-D'Amare] show that the ''B. subtilis'' ''[[glyQ]]-[[glyS]]'' [[T-box]] functions independently of any tRNA-binding protein. They demonstrate that the [[T-box]] detects the molecular volume of tRNA 3'-substituents..
+* Calcium is important for the activity of many many enzymes, and its cellular homeostasis is therefore important. Now, the previously unknown [[YetJ]] protein has been identified as a pH-sensitive calcium leak that allows reducing the inracellular calcium concentration. [http://www.ncbi.nlm.nih.gov/pubmed/24904158 Chang et al.] report the structure of [[YetJ]] and explain how two conserved Asp residues sense changes in the pH.
-** '''Relevant ''Subti''Wiki pages:''' [[T-box]], [[glyQ]]
+* '''Relevant ''Subti''Wiki pages:''' [[Metal ion homeostasis (K, Na, Ca, Mg)]], [[YetJ]]
-<pubmed> 24954903 </pubmed>
+<pubmed> 24904158 </pubmed>
 * [[Previous papers of the month]]