YkuN

• Description: flavodoxin, binds FMN, replaces ferredoxin under conditions of iron limitation, probably involved in electron transfer to nitric oxide synthase
  
  

Gene name	ykuN
Synonyms
Essential	no
Product	flavodoxin
Function	electron transfer
Gene expression levels in SubtiExpress: ykuN
Interactions involving this protein in SubtInteract: YkuN
Metabolic function and regulation of this protein in SubtiPathways: ykuN
MW, pI	17 kDa, 3.827
Gene length, protein length	474 bp, 158 aa
Immediate neighbours	ccpC, ykuO
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

electron transport/ other

This gene is a member of the following regulons

Fur regulon, NsrR regulon, ResD regulon

The gene

Basic information

• Locus tag: BSU14150

Database entries

• BsubCyc: BSU14150

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: flavodoxin-like domain (according to Swiss-Prot)

• Paralogous protein(s): YkuP

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors: FMN

• Effectors of protein activity:

• Interactions:
  • YkuN-BioI PubMed
  • YjiB-YkuN PubMed
  • Des-YkuN (electron transfer to Des) PubMed

• Localization:

Database entries

• BsubCyc: BSU14150

• Structure:

• UniProt: O34737

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ykuN-ykuO-ykuP PubMed

• Expression browser: ykuN PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced upon iron starvation (Fur) PubMed
  • expressed under anaerobic conditions (ResD) PubMed
  • induced by nitric oxide under anaerobic conditions (NsrR) PubMed

• Regulatory mechanism:
  • Fur: transcription repression PubMed
  • ResD: transcription activation PubMed
  • NsrR: transcription repression PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: