YtrE

• Description: ABC transporter (ATP-binding protein)
  
  

Gene name	ytrE
Synonyms
Essential	no
Product	ABC transporter (ATP-binding protein)
Function	unknown
Gene expression levels in SubtiExpress: ytrE
Interactions involving this protein in SubtInteract: YtrE
Metabolic function and regulation of this protein in SubtiPathways: ytrE
MW, pI	25 kDa, 5.98
Gene length, protein length	693 bp, 231 aa
Immediate neighbours	ytrF, ytrD
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, cold stress proteins, membrane proteins

This gene is a member of the following regulons

YtrA regulon

The gene

Basic information

• Locus tag: BSU30420

Database entries

• BsubCyc: BSU30420

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ABC transporter family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • (YtrB-YtrE)-(YtrC-YtrD)-YtrF PubMed

• Localization: cell membrane (via YtrC-YtrD) PubMed

Database entries

• BsubCyc: BSU30420

• Structure:

• UniProt: O34392

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: ytrG-ytrA-ytrB-ytrC-ytrD-ytrE-ytrF PubMed

• Expression browser: ytrE PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by ramoplanin (YtrA) PubMed
  • expressed early in the stationary phase PubMed
  • induced by cold shock (6-fold) PubMed
  • induced by antibiotics interfering with membrane-bound steps of cell wall biosynthesis PubMed

• Regulatory mechanism:
  • YtrA: transcription repression PubMed

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 143 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 306 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Michaela Wenzel, Bastian Kohl, Daniela Münch, Nadja Raatschen, H Bauke Albada, Leendert Hamoen, Nils Metzler-Nolte, Hans-Georg Sahl, Julia E Bandow
Proteomic response of Bacillus subtilis to lantibiotics reflects differences in interaction with the cytoplasmic membrane.
Antimicrob Agents Chemother: 2012, 56(11);5749-57
[PubMed:22926563] [WorldCat.org] [DOI] (I p)

Carsten L Beckering, Leif Steil, Michael H W Weber, Uwe Völker, Mohamed A Marahiel
Genomewide transcriptional analysis of the cold shock response in Bacillus subtilis.
J Bacteriol: 2002, 184(22);6395-402
[PubMed:12399512] [WorldCat.org] [DOI] (P p)

K I Yoshida, Y Fujita, S D Ehrlich
An operon for a putative ATP-binding cassette transport system involved in acetoin utilization of Bacillus subtilis.
J Bacteriol: 2000, 182(19);5454-61
[PubMed:10986249] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)