AzoR1

• Description: azoreductase, involved in quinone detoxification
  
  

Gene name	azoR1
Synonyms	yocJ
Essential	no
Product	azoreductase
Function	quinone detoxification
Gene expression levels in SubtiExpress: azoR1
MW, pI	22 kDa, 4.994
Gene length, protein length	624 bp, 208 aa
Immediate neighbours	bsrB, yocK
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

resistance against oxidative and electrophile stress, most abundant proteins

This gene is a member of the following regulons

YodB regulon

The gene

Basic information

• Locus tag: BSU19230

Database entries

• BsubCyc: BSU19230

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): AzoR2

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU19230

• Structure: 3P0R (from B. anthracis, 64% identity, 81% similarity)

• UniProt: O35022

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: azoR1 PubMed

• Sigma factor:

• Regulation:
  • induced by thiol-reactive compounds (catechol, menaquinone) (YodB) PubMed

• Regulatory mechanism:
  • YodB: transcription repression PubMed

• Additional information:
  • belongs to the 100 most abundant proteins PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 1232 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 1911 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: