SpoVG

• Description: negative effector of asymetric septation at the onset of sporulation
  
  

Gene name	spoVG
Synonyms
Essential	no
Product	negative effector of asymetric septation
Function	cell division, control of sporulation initiation
Gene expression levels in SubtiExpress: spoVG
MW, pI	10 kDa, 5.11
Gene length, protein length	291 bp, 97 aa
Immediate neighbours	yabJ, gcaD
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell division, sporulation/ other, phosphoproteins

This gene is a member of the following regulons

AbrB regulon, SigH regulon, SinR regulon

The gene

Basic information

• Locus tag: BSU00490

Database entries

• BsubCyc: BSU00490

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: spoVG family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylation on (Ser-66 OR Ser-67 OR Thr-68) PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU00490

• Structure: 2IA9

• UniProt: P28015

• KEGG entry: [3]

• E.C. number:

Additional information

• subject to Clp-dependent proteolysis upon glucose starvation PubMed

Expression and regulation

• Operon: spoVG PubMed

• Expression browser: spoVG PubMed

• Sigma factor: SigH PubMed

• Regulation: repressed by SinR PubMed
  • repressed by SinR PubMed
  • repressed during logrithmic growth (AbrB) PubMed

• Regulatory mechanism: SinR: transcription repression PubMed
  • SinR: transcription repression PubMed
  • AbrB: transcription repression PubMed

• Additional information: subject to Clp-dependent proteolysis upon glucose starvation PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 3775 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 4629 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: