YxeM

• Description: putative cysteine ABC transporter (binding protein), the yxeK-snaB-yxeM-yxeN-yxeO-sndB-yxeQ operon may be implicated in the utilization of a modified cysteine variant
  
  

Gene name	yxeM
Synonyms
Essential	no
Product	putative cysteine ABC transporter (binding protein)
Function	uptake of cysteine
Gene expression levels in SubtiExpress: yxeM
Interactions involving this protein in SubtInteract: YxeM
MW, pI	29 kDa, 9.086
Gene length, protein length	792 bp, 264 aa
Immediate neighbours	yxeN, yxeL
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, biosynthesis/ acquisition of amino acids, membrane proteins

This gene is a member of the following regulons

CymR regulon

The gene

Basic information

• Locus tag: BSU39500

Database entries

• BsubCyc: BSU39500

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: bacterial solute-binding protein 3 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YxeO-YxeN-YxeM PubMed

• Localization: associated to the membrane (via YxeN) PubMed

Database entries

• BsubCyc: BSU39500

• Structure:

• UniProt: P54952

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yxeK-snaB-yxeM-yxeN-yxeO-sndB-yxeQ PubMed

• Expression browser: yxeM PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed in the presence of cysteine (CymR) PubMed

• Regulatory mechanism:
  • CymR: transcription repression PubMed

• Additional information:
  • the amount of the mRNA is substantially decreased upon depletion of RNase Y PubMed

Biological materials

• Mutant:
  • 1A950 ( yxeM::cat), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: