YvgN

• Description: glyoxal reductase, general stress protein
  
  

Gene name	yvgN
Synonyms	yvsB
Essential	no
Product	glyoxal reductase
Function	unknown
Gene expression levels in SubtiExpress: yvgN
MW, pI	31 kDa, 5.066
Gene length, protein length	828 bp, 276 aa
Immediate neighbours	yvgM, yvgO
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

general stress proteins (controlled by SigB), resistance against oxidative and electrophile stress

This gene is a member of the following regulons

SigB regulon, SinR regulon

The gene

Basic information

• Locus tag: BSU33400

Database entries

• BsubCyc: BSU33400

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Lactaldehyde + NADP⁺ = methylglyoxal + NADPH (according to Swiss-Prot)

• Protein family: aldo/keto reductase family (according to Swiss-Prot)

• Paralogous protein(s): YtbE

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU33400

• Structure: 3B3E

• UniProt: O32210

• KEGG entry: [2]

• E.C. number: 1.1.1.283

Expression and regulation

• Operon:

• Expression browser: yvgN PubMed

• Sigma factor: SigB PubMed

• Regulation: induced by stress (SigB) PubMed, repressed by SinR PubMed
  • repressed by SinR PubMed

• Regulatory mechanism:
  • SinR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: