Difference between revisions of "RasP"
| Line 58: | Line 58: | ||
* mutants grow slower in liquid, are not competent, can’t activate [[SigW]], have [[cell division]] defects, and decreased long term survival {{PubMed|23687273}} | * mutants grow slower in liquid, are not competent, can’t activate [[SigW]], have [[cell division]] defects, and decreased long term survival {{PubMed|23687273}} | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU16560&redirect=T BSU16560] | ||
* '''DBTBS entry:''' no entry | * '''DBTBS entry:''' no entry | ||
| Line 98: | Line 99: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU16560&redirect=T BSU16560] | ||
* '''Structure:''' | * '''Structure:''' | ||
Revision as of 13:45, 2 April 2014
- Description: intramembrane protease, cleaves FtsL, RsiV and RsiW as well as signal peptides after release of the secreted proteins
| Gene name | rasP |
| Synonyms | yluC |
| Essential | no |
| Product | intramembrane protease |
| Function | control of cell division, and SigV and SigW activity |
| Gene expression levels in SubtiExpress: rasP | |
| Interactions involving this protein in SubtInteract: RasP | |
| MW, pI | 46 kDa, 5.14 |
| Gene length, protein length | 1266 bp, 422 aa |
| Immediate neighbours | ispC, proS |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
cell division, proteolysis, sigma factors and their control, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU16560
Phenotypes of a mutant
- defects in competence development, protein secretion and membrane protein production PubMed
- mutants grow slower in liquid, are not competent, can’t activate SigW, have cell division defects, and decreased long term survival PubMed
Database entries
- BsubCyc: BSU16560
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: peptidase M50B family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane PubMed
Database entries
- BsubCyc: BSU16560
- Structure:
- UniProt: O31754
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Thomas Wiegert, University of Bayreuth, Germany Homepage
Your additional remarks
References
Reviews
Original publications
