Difference between revisions of "MgtE"

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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU13300&redirect=T BSU13300]
  
 
* '''DBTBS entry:''' no entry
 
* '''DBTBS entry:''' no entry
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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU13300&redirect=T BSU13300]
  
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2QBZ 2QBZ] (the mgtE riboswitch)
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2QBZ 2QBZ] (the mgtE riboswitch)

Revision as of 13:31, 2 April 2014

  • Description: primary magnesium transporter

Gene name mgtE
Synonyms ykoK
Essential no
Product primary magnesium transporter
Function magnesium uptake
Gene expression levels in SubtiExpress: mgtE
MW, pI 50 kDa, 4.609
Gene length, protein length 1353 bp, 451 aa
Immediate neighbours ykzO, tnrA
Sequences Protein DNA DNA_with_flanks
Genetic context
YkoK context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MgtE expression.png















Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), membrane proteins

This gene is a member of the following regulons

M-box

The gene

Basic information

  • Locus tag: BSU13300

Phenotypes of a mutant

  • a mgtE mutant has a growth defect on rich media, this can be suppressed by the addition of 25 mM Mg2+, moreover the mutant grows well on minimal medim in the presence of citrate PubMed
  • a mgtE yfjQ mutant does not grow on rich media, this can be suppressed by the addition of 25 mM Mg2+, moreover the mutant grows well on minimal medim in the presence of citrate PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: SLC41A transporter family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure: 2QBZ (the mgtE riboswitch)
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation: induced at low magnesium concentration (M-box) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References