Difference between revisions of "GuaA"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU06360&redirect=T BSU06360] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/guaA.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/guaA.html] | ||
| Line 89: | Line 90: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU06360&redirect=T BSU06360] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2YWB 2YWB] (from ''Thermus thermophilus hb8'', 45% identity, 57% similarity) | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2YWB 2YWB] (from ''Thermus thermophilus hb8'', 45% identity, 57% similarity) | ||
Revision as of 13:07, 2 April 2014
- Description: GMP synthase (glutamine-hydrolysing)
| Gene name | guaA |
| Synonyms | guaB |
| Essential | no |
| Product | GMP synthetase (glutamine-hydrolysing) |
| Function | biosynthesis of GMP |
| Gene expression levels in SubtiExpress: guaA | |
| Metabolic function and regulation of this protein in SubtiPathways: guaA | |
| MW, pI | 57 kDa, 4.747 |
| Gene length, protein length | 1539 bp, 513 aa |
| Immediate neighbours | yebA, pbuG |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides, most abundant proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU06360
Phenotypes of a mutant
Database entries
- BsubCyc: BSU06360
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + xanthosine 5'-phosphate + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
- the enzyme is inhibited by guanosine tetraphosphate (stringent response) PubMed
Database entries
- BsubCyc: BSU06360
- Structure: 2YWB (from Thermus thermophilus hb8, 45% identity, 57% similarity)
- UniProt: P29727
- KEGG entry: [3]
- E.C. number: 6.3.5.2
Additional information
Expression and regulation
- Operon: guaA PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
- belongs to the 100 most abundant proteins PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
