YclN

• Description: petrobactin (3.4-catecholate siderophore) ABC transporter (permease)
  
  

Gene name	yclN
Synonyms
Essential	no
Product	petrobactin ABC transporter (permease)
Function	acquisition of iron
Gene expression levels in SubtiExpress: yclN
Interactions involving this protein in SubtInteract: YclN
MW, pI	34 kDa, 9.817
Gene length, protein length	948 bp, 316 aa
Immediate neighbours	yclM, yclO
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, acquisition of iron, iron metabolism, membrane proteins

This gene is a member of the following regulons

Fur regulon

The gene

Basic information

• Locus tag: BSU03800

Database entries

• BsubCyc: BSU03800

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: uptake of the siderophore petrobactin PubMed

• Protein family: FecCD subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YclP-(YclN-YclO)-YclQ PubMed

• Localization: cell membrane PubMed

Database entries

• BsubCyc: BSU03800

• Structure:

• UniProt: P94418

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yclN-yclO-yclP-yclQ PubMed

• Expression browser: yclN PubMed

• Sigma factor:

• Regulation:
  • induced upon iron starvation (Fur) PubMed

• Regulatory mechanism:
  • Fur: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Anna M Zawadzka, Youngchang Kim, Natalia Maltseva, Rita Nichiporuk, Yao Fan, Andrzej Joachimiak, Kenneth N Raymond
Characterization of a Bacillus subtilis transporter for petrobactin, an anthrax stealth siderophore.
Proc Natl Acad Sci U S A: 2009, 106(51);21854-9
[PubMed:19955416] [WorldCat.org] [DOI] (I p)

Noel Baichoo, Tao Wang, Rick Ye, John D Helmann
Global analysis of the Bacillus subtilis Fur regulon and the iron starvation stimulon.
Mol Microbiol: 2002, 45(6);1613-29
[PubMed:12354229] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)