NusG

• Description: transcription antitermination and pausing factor
  
  

Gene name	nusG
Synonyms
Essential	no
Product	transcription antitermination and pausing factor
Function	transcription
Gene expression levels in SubtiExpress: nusG
Interactions involving this protein in SubtInteract: NusG
MW, pI	19 kDa, 5.252
Gene length, protein length	531 bp, 177 aa
Immediate neighbours	secE, rplK
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription

The gene

Basic information

• Locus tag: BSU01010

Database entries

• BsubCyc: BSU01010

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: KOW domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • Rho-NusG (C-terminal domain) (based on data for E. coli) PubMed

• Localization:

Database entries

• BsubCyc: BSU01010

• Structure:

• UniProt: Q06795

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: nusG PubMed

• Sigma factor:

• Regulation:
  • strongly repressed in response to glucose starvation in M9 medium PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Alexander V Yakhnin, Paul Babitzke
NusG/Spt5: are there common functions of this ubiquitous transcription elongation factor?
Curr Opin Microbiol: 2014, 18;68-71
[PubMed:24632072] [WorldCat.org] [DOI] (I p)