Difference between revisions of "NagB"

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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactor(s):'''
+
* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
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* '''Regulation:'''  
 
* '''Regulation:'''  
** induced in the presence of N-acetylglucosamine ([[NagR]]) {{PubMed|21602348}}
+
** induced in the presence of N-acetylglucosamine ([[NagR]]) {{PubMed|24673833,21602348}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
** [[NagR]]: transcription repression {{PubMed|21602348}}
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** [[NagR]]: transcription repression {{PubMed|24673833,21602348}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
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=References=
 
=References=
<pubmed>6174502,15755726 21821766 21602348 23667565 23876412</pubmed>
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<pubmed>6174502,15755726 21821766 21602348 23667565 24673833,23876412</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 10:51, 31 March 2014

  • Description: glucosamine-6-phosphate deaminase

Gene name nagB
Synonyms
Essential no
Product glucosamine-6-phosphate deaminase
Function N-acetylglucosamine utilization
Gene expression levels in SubtiExpress: nagB
Metabolic function and regulation of this protein in SubtiPathways:
nagB
MW, pI 26 kDa, 5.717
Gene length, protein length 726 bp, 242 aa
Immediate neighbours nagA, nagR
Sequences Protein DNA DNA_with_flanks
Genetic context
NagB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NagB expression.png















Categories containing this gene/protein

cell wall degradation/ turnover, utilization of specific carbon sources

This gene is a member of the following regulons

NagR regulon

The gene

Basic information

  • Locus tag: BSU35020

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

  • A mutation was found in this gene after evolution under relaxed selection for sporulation PubMed

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: D-glucosamine 6-phosphate + H2O = D-fructose 6-phosphate + NH3 (according to Swiss-Prot)
  • Protein family: NagB subfamily (according to Swiss-Prot)
  • Paralogous protein(s): GamA

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced in the presence of N-acetylglucosamine (NagR) PubMed
  • Regulatory mechanism:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References