Difference between revisions of "RplB"
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| − | * '''Description:''' [[ribosomal protein]] | + | * '''Description:''' [[ribosomal protein]] L2, required for assembly of [[RplP]] into the 50S subunit of the [[ribosome]]<br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| − | + | * essential {{PubMed|23002217,12682299}} | |
| − | essential {{PubMed|23002217,12682299}} | + | * a H142L mutation results in a temperature-sensitive phenotype and is acompanied by growth and [[sporulation]] defects, the mutation can be suppressed by increased expression of ''[[yaaA]]'' {{PubMed|24637032}} |
=== Database entries === | === Database entries === | ||
| Line 84: | Line 84: | ||
* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
| + | ** [[RplB]]-[[23S rRNA]] {{PubMed|24637032}} | ||
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
| Line 142: | Line 143: | ||
=References= | =References= | ||
| − | <pubmed> 19653700 9371452 11948165 8635744 10075918 23249812 23002217</pubmed> | + | <pubmed> 19653700 9371452 11948165 8635744 10075918 23249812 23002217 24637032</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 12:05, 19 March 2014
- Description: ribosomal protein L2, required for assembly of RplP into the 50S subunit of the ribosome
| Gene name | rplB |
| Synonyms | |
| Essential | yes PubMed |
| Product | ribosomal protein L2 (BL2) |
| Function | translation |
| Gene expression levels in SubtiExpress: rplB | |
| Interactions involving this protein in SubtInteract: RplB | |
| MW, pI | 30 kDa, 11.013 |
| Gene length, protein length | 831 bp, 277 aa |
| Immediate neighbours | rplW, rpsS |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
translation, essential genes, universally conserved proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU01190
Phenotypes of a mutant
- essential PubMed
- a H142L mutation results in a temperature-sensitive phenotype and is acompanied by growth and sporulation defects, the mutation can be suppressed by increased expression of yaaA PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: ribosomal protein L2P family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- Structure: 1RL2 (L2 RNA-binding domain, Geobacillus stearothermophilus)
- UniProt: P42919
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon: rpsJ-rplC-rplD-rplW-rplB-rpsS-rplV-rpsC-rplP-rpmC-rpsQ-rplN-rplX-rplE-rpsN-rpsH-rplF-rplR-rpsE-rpmD-rplO PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
