Difference between revisions of "MreBH"
| Line 45: | Line 45: | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| − | {{SubtiWiki regulon|[[SigI regulon]]}} | + | {{SubtiWiki regulon|[[SigI regulon]]}}, |
| + | {{SubtiWiki regulon|[[WalR regulon]]}} | ||
=The gene= | =The gene= | ||
| Line 80: | Line 81: | ||
* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| Line 123: | Line 124: | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| − | |||
** expression is increased in an ''[[ugtP]]'' mutant {{PubMed|22362028}} | ** expression is increased in an ''[[ugtP]]'' mutant {{PubMed|22362028}} | ||
| + | ** induced at high temperature ([[SigI]], [[WalR]]) {{PubMed|24125693,18156261}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[WalR]]: transcription activation {{PubMed|24125693}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 146: | Line 148: | ||
=Labs working on this gene/protein= | =Labs working on this gene/protein= | ||
| − | |||
=Your additional remarks= | =Your additional remarks= | ||
| Line 154: | Line 155: | ||
<pubmed> 17064365, 20566861 21636744,21636745 22362028 </pubmed> | <pubmed> 17064365, 20566861 21636744,21636745 22362028 </pubmed> | ||
==Other original publications== | ==Other original publications== | ||
| − | <pubmed>16950129,19643765 ,16950129 18156261, 19659933 21091501 22069484 23879732 23869552</pubmed> | + | <pubmed>16950129,19643765 ,16950129 18156261, 19659933 21091501 22069484 23879732 23869552 24125693</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 10:33, 23 December 2013
- Description: cell shape-determining protein, forms filaments, the polymers control/restrict the mobility of the cell wall elongation enzyme complex, , required for LytE activity
| Gene name | mreBH |
| Synonyms | |
| Essential | no |
| Product | cell shape-determining protein |
| Function | cell shape determation |
| Gene expression levels in SubtiExpress: mreBH | |
| Interactions involving this protein in SubtInteract: MreBH | |
| MW, pI | 35 kDa, 5.239 |
| Gene length, protein length | 1005 bp, 335 aa |
| Immediate neighbours | ykpC, abh |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
cell shape, heat shock proteins, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU14470
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: ftsA/mreB family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
- Localization:
- during logarithmic growth, MreBH forms discrete patches thst move processively along peripheral tracks perpendicular to the cell axis PubMed
- forms transverse bands as cells enter the stationary phase PubMed
- close to the inner surface of the cytoplasmic membrane PubMed
- reports on helical structures formed by MreBH PubMed seem to be misinterpretation of data PubMed
- normal localization depends on the presence of glucolipids, MreB forms irregular clusters in an ugtP mutant PubMed
Database entries
- Structure:
- UniProt: P39763
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Localization
Other original publications
