YxlC

• Description: putative anti-SigY protein
  
  

Gene name	yxlC
Synonyms
Essential	yes PubMed
Product	putative anti-SigY protein
Function	control of SigY activity
Gene expression levels in SubtiExpress: yxlC
Interactions involving this protein in SubtInteract: YxlC
MW, pI	11 kDa, 9.494
Gene length, protein length	318 bp, 106 aa
Immediate neighbours	yxlD, sigY
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sigma factors and their control, cell envelope stress proteins (controlled by SigM, V, W, X, Y), membrane proteins, essential genes

This gene is a member of the following regulons

SigY regulon

The gene

Basic information

• Locus tag: BSU38690

Phenotypes of a mutant

• essential PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • SigY- YxlC PubMed

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P94371

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: sigY-yxlC-yxlD-yxlE-yxlF-yxlG PubMed

• Expression browser: yxlC PubMed

• Sigma factor: SigY PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Rebecca Mendez, Alba Gutierrez, Jasmin Reyes, Leticia Márquez-Magaña
The extracytoplasmic function sigma factor SigY is important for efficient maintenance of the Spβ prophage that encodes sublancin in Bacillus subtilis.
DNA Cell Biol: 2012, 31(6);946-55
[PubMed:22400495] [WorldCat.org] [DOI] (I p)

Mika Yoshimura, Kei Asai, Yoshito Sadaie, Hirofumi Yoshikawa
Interaction of Bacillus subtilis extracytoplasmic function (ECF) sigma factors with the N-terminal regions of their potential anti-sigma factors.
Microbiology (Reading): 2004, 150(Pt 3);591-599
[PubMed:14993308] [WorldCat.org] [DOI] (P p)

Shigeo Tojo, Masayuki Matsunaga, Takashi Matsumoto, Choong-Min Kang, Hirotake Yamaguchi, Kei Asai, Yoshito Sadaie, Ken-ichi Yoshida, Yasutaro Fujita
Organization and expression of the Bacillus subtilis sigY operon.
J Biochem: 2003, 134(6);935-46
[PubMed:14769884] [WorldCat.org] [DOI] (P p)

Min Cao, Letal Salzberg, Ching Sung Tsai, Thorsten Mascher, Carla Bonilla, Tao Wang, Rick W Ye, Leticia Márquez-Magaña, John D Helmann
Regulation of the Bacillus subtilis extracytoplasmic function protein sigma(Y) and its target promoters.
J Bacteriol: 2003, 185(16);4883-90
[PubMed:12897008] [WorldCat.org] [DOI] (P p)