YclK

• Description: two-component sensor kinase
  
  

Gene name	yclK
Synonyms
Essential	no
Product	two-component sensor kinase
Function	unknown
Gene expression levels in SubtiExpress: yclK
Interactions involving this protein in SubtInteract: YclK
MW, pI	54 kDa, 6.152
Gene length, protein length	1419 bp, 473 aa
Immediate neighbours	yclJ, rapC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

protein modification, transcription factors and their control, membrane proteins, phosphoproteins

This gene is a member of the following regulons

ResD regulon

The gene

Basic information

• Locus tag: BSU03760

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of YclJ

• Protein family:

• Paralogous protein(s): CssS, YkoH, KinE, YvrG

Extended information on the protein

• Kinetic information:

• Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain

• Modification: autophosphorylation on a His residue

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YclK-YclJ (putative)

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P94414

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yclJ-yclK PubMed

• Expression browser: yclK PubMed

• Sigma factor:

• Regulation:
  • expressed under anaerobic conditions (ResD) PubMed

• Regulatory mechanism:
  • ResD: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Elisabeth Härtig, Hao Geng, Anja Hartmann, Angela Hubacek, Richard Münch, Rick W Ye, Dieter Jahn, Michiko M Nakano
Bacillus subtilis ResD induces expression of the potential regulatory genes yclJK upon oxygen limitation.
J Bacteriol: 2004, 186(19);6477-84
[PubMed:15375128] [WorldCat.org] [DOI] (P p)

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)