Difference between revisions of "Dps"

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* '''Description:''' iron storage protein, general stress protein, resistance against ethanol stress and survival at low temperatures  <br/><br/>
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* '''Description:''' iron storage protein, general stress protein, resistance against ethanol and paraquat stresses stress and survival at low temperatures  <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Product''' || mini-ferritin
 
|style="background:#ABCDEF;" align="center"| '''Product''' || mini-ferritin
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || iron storage
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|style="background:#ABCDEF;" align="center"|'''Function''' || iron storage, survival of of stress conditions
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30650 dps]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30650 dps]
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{{SubtiWiki category|[[acquisition of iron]]}},
 
{{SubtiWiki category|[[acquisition of iron]]}},
 
{{SubtiWiki category|[[iron metabolism]]}},
 
{{SubtiWiki category|[[iron metabolism]]}},
{{SubtiWiki category|[[general stress proteins (controlled by SigB)]]}}
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{{SubtiWiki category|[[general stress proteins (controlled by SigB)]]}},
 +
{{SubtiWiki category|[[resistance against oxidative and electrophile stress]]}}
  
 
= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dps_3136238_3136675_-1 dps] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dps_3136238_3136675_-1 dps] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigB]] {{PubMed|9393687,15805528}}
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* '''[[Sigma factor]]:''' [[SigB]] {{PubMed|9393687,15805528}}
  
 
* '''Regulation:'''   
 
* '''Regulation:'''   
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<pubmed>15222465  </pubmed>
 
<pubmed>15222465  </pubmed>
 
==Original publications==
 
==Original publications==
<pubmed>9393687,9013563 ,15805528, </pubmed>
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<pubmed>9393687,9013563 ,15805528,22582280 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 19:05, 15 September 2013

  • Description: iron storage protein, general stress protein, resistance against ethanol and paraquat stresses stress and survival at low temperatures

Gene name dps
Synonyms ytkB
Essential no
Product mini-ferritin
Function iron storage, survival of of stress conditions
Gene expression levels in SubtiExpress: dps
MW, pI 16 kDa, 4.444
Gene length, protein length 435 bp, 145 aa
Immediate neighbours ytkC, ytzI
Sequences Protein DNA DNA_with_flanks
Genetic context
Dps context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Dps expression.png















Categories containing this gene/protein

acquisition of iron, iron metabolism, general stress proteins (controlled by SigB), resistance against oxidative and electrophile stress

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

  • Locus tag: BSU30650

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: dps family (according to Swiss-Prot)
  • Paralogous protein(s): MrgA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications

Alexander Reder, Dirk Höper, Ulf Gerth, Michael Hecker
Contributions of individual σB-dependent general stress genes to oxidative stress resistance of Bacillus subtilis.
J Bacteriol: 2012, 194(14);3601-10
[PubMed:22582280] [WorldCat.org] [DOI] (I p)

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

H Antelmann, S Engelmann, R Schmid, A Sorokin, A Lapidus, M Hecker
Expression of a stress- and starvation-induced dps/pexB-homologous gene is controlled by the alternative sigma factor sigmaB in Bacillus subtilis.
J Bacteriol: 1997, 179(23);7251-6
[PubMed:9393687] [WorldCat.org] [DOI] (P p)

M Bozzi, G Mignogna, S Stefanini, D Barra, C Longhi, P Valenti, E Chiancone
A novel non-heme iron-binding ferritin related to the DNA-binding proteins of the Dps family in Listeria innocua.
J Biol Chem: 1997, 272(6);3259-65
[PubMed:9013563] [WorldCat.org] [DOI] (P p)