Difference between revisions of "AdaB"

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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[DNA repair/ recombination]]}}
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{{SubtiWiki category|[[DNA repair/ recombination]]}},
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{{SubtiWiki category|[[prophage 1]]}}
  
 
= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=adaB_204351_204890_1 adaB] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=adaB_204351_204890_1 adaB] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/2120677 PubMed]
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* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/2120677 PubMed]
  
 
* '''Regulation:''' positive control by [[AdaA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/2120677 PubMed]
 
* '''Regulation:''' positive control by [[AdaA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/2120677 PubMed]

Revision as of 11:24, 11 September 2013

  • Description: O6-methylguanine-DNA methyltransferase

Gene name adaB
Synonyms
Essential no
Product O6-methylguanine-DNA methyltransferase
Function adaptive response to alkylative DNA damage
Gene expression levels in SubtiExpress: adaB
MW, pI 19 kDa, 6.152
Gene length, protein length 537 bp, 179 aa
Immediate neighbours adaA, ndhF
Sequences Protein DNA DNA_with_flanks
Genetic context
AdaB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
AdaB expression.png















Categories containing this gene/protein

DNA repair/ recombination, prophage 1

This gene is a member of the following regulons

AdaA regulon

The gene

Basic information

  • Locus tag: BSU01820

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: DNA (containing 6-O-methylguanine) + protein L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine (according to Swiss-Prot)
  • Protein family: MGMT family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References