Difference between revisions of "DltA"
| Line 58: | Line 58: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
** increased sensitivity to lysozyme {{PubMed|21856855}} | ** increased sensitivity to lysozyme {{PubMed|21856855}} | ||
| + | * more sensitive to nisin {{PubMed|23980836}} | ||
| + | |||
=== Database entries === | === Database entries === | ||
| Line 111: | Line 113: | ||
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dltA_3952275_3953786_1 dltA] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dltA_3952275_3953786_1 dltA] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigD]] {{PubMed|7797557}}, [[SigM]] {{PubMed|18179421}}, [[SigX]] {{PubMed|14762009}} | + | * '''[[Sigma factor]]:''' [[SigD]] {{PubMed|7797557}}, [[SigM]] {{PubMed|18179421}}, [[SigX]] {{PubMed|14762009}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| Line 145: | Line 147: | ||
=References= | =References= | ||
| − | + | <pubmed>14762009,15955059,18784082,23980836,7797557, 19324056, 16306698 21856855,21926231</pubmed> | |
| − | <pubmed>14762009,15955059,18784082,,7797557, 19324056, 16306698 </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 18:14, 30 August 2013
- Description: D-alanyl-D-alanine carrier protein ligase, alanylation of teichoic acid provides some resistance against positively charged antimicrobial peptides
| Gene name | dltA |
| Synonyms | ipa-5r, dae |
| Essential | no |
| Product | D-alanyl-D-alanine carrier protein ligase |
| Function | biosynthesis of teichoic acid |
| Gene expression levels in SubtiExpress: dltA | |
| MW, pI | 55 kDa, 4.929 |
| Gene length, protein length | 1509 bp, 503 aa |
| Immediate neighbours | ywzH, dltB |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
cell wall synthesis, biosynthesis of cell wall components, cell envelope stress proteins (controlled by SigM, V, W, X, Y)
This gene is a member of the following regulons
SigD regulon, SigM regulon, SigX regulon, Spo0A regulon, stringent response, YvrHb regulon
The gene
Basic information
- Locus tag: BSU38500
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + D-alanine + poly(ribitol phosphate) = AMP + diphosphate + O-D-alanyl-poly(ribitol phosphate) (according to Swiss-Prot)
- Protein family: DltA subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 3E7X
- UniProt: P39581
- KEGG entry: [3]
- E.C. number: 6.1.1.13
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Mohamed Marahiel, Marburg University, Germany homepage
Your additional remarks
References
