Difference between revisions of "TcyK"

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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
 
{{SubtiWiki regulon|[[CymR regulon]]}},
 
{{SubtiWiki regulon|[[CymR regulon]]}},
{{SubtiWiki regulon|[[YtlI regulon]]}}
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{{SubtiWiki regulon|[[AscR regulon]]}}
  
 
=The gene=
 
=The gene=
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=Expression and regulation=
 
=Expression and regulation=
* '''Operon:''' ''[[ytmI]]-[[tcyJ]]-[[tcyK]]-[[tcyL]]-[[tcyM]]-[[tcyN]]-[[ytmO]]-[[ytnI]]-[[ytnJ]]-[[ribR]]-[[ytnL]]-[[ytnM]]'' {{PubMed|15668000}}
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* '''Operon:''' ''[[snaA]]-[[tcyJ]]-[[tcyK]]-[[tcyL]]-[[tcyM]]-[[tcyN]]-[[cmoO]]-[[cmoI]]-[[cmoJ]]-[[ribR]]-[[sndA]]-[[ytnM]]'' {{PubMed|15668000}}
  
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=tcyK_3006600_3007412_-1 tcyK] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=tcyK_3006600_3007412_-1 tcyK] {{PubMed|22383849}}
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* '''Regulation:'''  
 
* '''Regulation:'''  
 
** repressed in the presence of cysteine ([[CymR]]) {{PubMed|16109943}}
 
** repressed in the presence of cysteine ([[CymR]]) {{PubMed|16109943}}
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** induced in the presence of S-methyl-cysteine ([[AscR]]) {{PubMed|23944997}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 
** [[CymR]]: transcription repression {{PubMed|16109943}}
 
** [[CymR]]: transcription repression {{PubMed|16109943}}
** [[YtlI]]: transcription activation {{PubMed|16109943}}
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** [[AscR]]: transcription activation {{PubMed|16109943}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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=References=
 
=References=
 
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<pubmed>15262924,10092453,16109943,12193636, 15668000 15272571 23944997</pubmed>
<pubmed>15262924,10092453,16109943,12193636, 15668000 </pubmed>
 
'''Additional publications:''' {{PubMed|15272571}}
 
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 10:23, 18 August 2013

Gene name tcyK
Synonyms ytmK
Essential no
Product cystine ABC transporter (binding protein)
Function cystine uptake
Gene expression levels in SubtiExpress: tcyK
Interactions involving this protein in SubtInteract: TcyK
Metabolic function and regulation of this protein in SubtiPathways:
Riboflavin / FAD
MW, pI 30 kDa, 9.009
Gene length, protein length 810 bp, 270 aa
Immediate neighbours tcyL, tcyJ
Sequences Protein DNA DNA_with_flanks
Genetic context
YtmK context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
TcyK expression.png















Categories containing this gene/protein

ABC transporters, biosynthesis/ acquisition of amino acids, membrane proteins

This gene is a member of the following regulons

CymR regulon, AscR regulon

The gene

Basic information

  • Locus tag: BSU29370

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: bacterial solute-binding protein 3 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of cysteine (CymR) PubMed
    • induced in the presence of S-methyl-cysteine (AscR) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References