Difference between revisions of "Cofactors"

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 +
= NAD(+) =
 +
* [[LplD]]
 +
 
= Copper =
 
= Copper =
 
* [[CtaC]] (Cu(A))
 
* [[CtaC]] (Cu(A))
Line 8: Line 11:
 
* [[UreA]]-[[UreB]]-[[UreC]] (urease), the nickel ion binds the active site in [[UreC]]
 
* [[UreA]]-[[UreB]]-[[UreC]] (urease), the nickel ion binds the active site in [[UreC]]
 
<pubmed> 19363030 23539618 20442959 </pubmed>
 
<pubmed> 19363030 23539618 20442959 </pubmed>
 +
 +
= Manganese =
 +
* [[LplD]]
  
 
= Heme A =  
 
= Heme A =  

Revision as of 15:26, 16 August 2013

NAD(+)

Copper

Nickel

Mark A Farrugia, Lee Macomber, Robert P Hausinger
Biosynthesis of the urease metallocenter.
J Biol Chem: 2013, 288(19);13178-85
[PubMed:23539618] [WorldCat.org] [DOI] (I p)

Harini Kaluarachchi, Kim C Chan Chung, Deborah B Zamble
Microbial nickel proteins.
Nat Prod Rep: 2010, 27(5);681-94
[PubMed:20442959] [WorldCat.org] [DOI] (I p)

Stephen W Ragsdale
Nickel-based Enzyme Systems.
J Biol Chem: 2009, 284(28);18571-5
[PubMed:19363030] [WorldCat.org] [DOI] (P p)


Manganese

Heme A

Thiamine pyrophosphate

E1 subunits of ketoacid dehydrogenases/ acetoin dehydrogenase

Lipoic acid

E2 subunits of ketoacid dehydrogenases/ acetoin dehydrogenase

H protein of the glycine cleavage system

  • GcvH (also required for LipL-catalyzed octanoyl transfer from AcpA to the E2s)

pyridoxyl phosphate

tetrahydrofalate