Difference between revisions of "QoxB"

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* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactor(s):'''
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* '''Cofactor(s):''' Cu(B) {{PubMed|10837475}}
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
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=References=
 
=References=
'''Additional publications:''' {{PubMed|22211522}}
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<pubmed> 11073895 1316894 20351111,10551842,18763711, 21821766 10837475 22211522</pubmed>
<pubmed> 11073895 1316894 20351111,10551842,18763711, 21821766</pubmed>
 
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 18:24, 11 August 2013

  • Description: cytochrome aa3 quinol oxidase (subunit I)

Gene name qoxB
Synonyms ipa-38d
Essential no
Product cytochrome aa3 quinol oxidase (subunit I)
Function respiration
Gene expression levels in SubtiExpress: qoxB
MW, pI 73 kDa, 8.848
Gene length, protein length 1947 bp, 649 aa
Immediate neighbours qoxC, qoxA
Sequences Protein DNA DNA_with_flanks
Genetic context
QoxB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
QoxB expression.png















Categories containing this gene/protein

respiration, membrane proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU38160

Phenotypes of a mutant

  • inactivation of qoxB restores beta-lactam resistance in a sigM mutant PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

  • A mutation was found in this gene after evolution under relexed selection for sporulation PubMed

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Ubiquinol-8 + O2 = Ubiquinone-8 + H2O (according to Swiss-Prot)
  • Protein family: heme-copper respiratory oxidase family (according to Swiss-Prot)
  • Paralogous protein(s): CtaD

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References