Difference between revisions of "DgrA"

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m (Jstuelk moved page YpfA to DgrA: 23893111)
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|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''ypfA''
+
|''dgrA''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''jofA ''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ypfA, jofA ''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[MotA]] activity
 
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[MotA]] activity
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU22910 ypfA]
+
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU22910 DgrA]
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/YpfA YpfA]
+
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/DgrA DgrA]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 24 kDa, 7.878   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 24 kDa, 7.878   
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* '''[[SubtInteract|Interactions]]:'''  
 
* '''[[SubtInteract|Interactions]]:'''  
** [[YpfA]]-[[MotA]] {{PubMed|22821967}}
+
** [[DgrA]]-[[MotA]] {{PubMed|22821967}}
  
 
* '''[[Localization]]:'''
 
* '''[[Localization]]:'''
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* '''Operon:'''  
 
* '''Operon:'''  
  
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ypfA_2397019_2397672_-1 ypfA] {{PubMed|22383849}}
+
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ypfA_2397019_2397672_-1 dgrA] {{PubMed|22383849}}
  
 
* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
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=References=
 
=References=
<pubmed> 22821967</pubmed>
+
<pubmed> 23893111 22821967</pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 10:30, 10 August 2013

  • Description: c-di-GMP receptor protein, inhibits motility during entry into sporulation

Gene name dgrA
Synonyms ypfA, jofA
Essential no
Product c-di-GMP receptor protein
Function control of MotA activity
Gene expression levels in SubtiExpress: DgrA
Interactions involving this protein in SubtInteract: DgrA
MW, pI 24 kDa, 7.878
Gene length, protein length 651 bp, 217 aa
Immediate neighbours ypfB, ypeB
Sequences Protein DNA DNA_with_flanks
Genetic context
YpfA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YpfA expression.png















Categories containing this gene/protein

motility and chemotaxis

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU22910

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
    • contains a C-terminal PilZ domain PubMed
  • Modification:
  • Effectors of protein activity:
    • binding of c-di-GMP stimulates the inhibitory interaction with MotA PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Xiaohui Gao, Sampriti Mukherjee, Paige M Matthews, Loubna A Hammad, Daniel B Kearns, Charles E Dann
Functional characterization of core components of the Bacillus subtilis cyclic-di-GMP signaling pathway.
J Bacteriol: 2013, 195(21);4782-92
[PubMed:23893111] [WorldCat.org] [DOI] (I p)

Yun Chen, Yunrong Chai, Jian-hua Guo, Richard Losick
Evidence for cyclic Di-GMP-mediated signaling in Bacillus subtilis.
J Bacteriol: 2012, 194(18);5080-90
[PubMed:22821967] [WorldCat.org] [DOI] (I p)