Difference between revisions of "GerW"
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| − | * '''Description:''' | + | * '''Description:''' [[germination]] protein, essential for [[germination]] in response to L-alanine <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || [[germination]] protein |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || [[germination]] in response to L-alanine |
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU29500 | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU29500 gerW] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 16 kDa, 4.988 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 16 kDa, 4.988 | ||
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<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
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| − | |||
| − | |||
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<br/><br/> | <br/><br/> | ||
= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| − | {{SubtiWiki category|[[ | + | {{SubtiWiki category|[[germination]]}} |
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| Line 54: | Line 50: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| + | * no [[germination]] in response to l-alanine {{PubMed|23921501}} | ||
=== Database entries === | === Database entries === | ||
| Line 62: | Line 59: | ||
=== Additional information=== | === Additional information=== | ||
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| Line 88: | Line 83: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
| − | * '''Localization:''' | + | * '''[[Localization]]:''' |
=== Database entries === | === Database entries === | ||
| Line 106: | Line 101: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''[[ytfI]]-[[ | + | * '''Operon:''' ''[[ytfI]]-[[gerW]]'' {{PubMed|9387221}} |
| − | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ytfJ_3018309_3018764_-1 | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ytfJ_3018309_3018764_-1 gerW] {{PubMed|22383849}} |
| − | * '''Sigma factor:''' [[SigF]] {{PubMed|16497325}} | + | * '''[[Sigma factor]]:''' [[SigF]] {{PubMed|23921501,16497325}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** expressed early during sporulation in the forespore ([[SigF]]) {{PubMed|16497325}} | + | ** expressed early during sporulation in the forespore ([[SigF]]) {{PubMed|23921501,16497325}} |
** repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed] | ** repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed] | ||
| Line 140: | Line 135: | ||
=References= | =References= | ||
| − | <pubmed>16497325,9387221,12107147, </pubmed> | + | <pubmed>16497325,9387221,12107147, 23921501 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:03, 8 August 2013
- Description: germination protein, essential for germination in response to L-alanine
| Gene name | gerW |
| Synonyms | ytfJ |
| Essential | no |
| Product | germination protein |
| Function | germination in response to L-alanine |
| Gene expression levels in SubtiExpress: gerW | |
| MW, pI | 16 kDa, 4.988 |
| Gene length, protein length | 453 bp, 151 aa |
| Immediate neighbours | tpx, ytfI |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU29500
Phenotypes of a mutant
- no germination in response to l-alanine PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34806
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Ritsuko Kuwana, Hiromu Takamatsu
The GerW protein is essential for L-alanine-stimulated germination of Bacillus subtilis spores.
J Biochem: 2013, 154(5);409-17
[PubMed:23921501]
[WorldCat.org]
[DOI]
(I p)
Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325]
[WorldCat.org]
[DOI]
(P p)
Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147]
[WorldCat.org]
[DOI]
(P p)
Alia Lapidus, Nathalie Galleron, Alexei Sorokin, S Dusko Ehrlich
Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region.
Microbiology (Reading): 1997, 143 ( Pt 11);3431-3441
[PubMed:9387221]
[WorldCat.org]
[DOI]
(P p)
