YoyC

• Description: unknown
  
  

Gene name	yoyC
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: yoyC
MW, pI	11 kDa, 5.910
Gene length, protein length	276 bp, 92 aa
Immediate neighbours	yojF, yojE
Sequences	Protein DNA DNA_with_flanks
Genetic context File:YoyC context.gif
Expression at a glance   PubMed

Categories containing this gene/protein

proteins of unknown function

This gene is a member of the following regulons

Spx regulon

The gene

Basic information

• Locus tag: BSU19479

Database entries

• DBTBS entry: no entry

• SubtiList entry: no entry

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O68260

• KEGG entry:

• E.C. number:

Expression and regulation

• Operon:
  • yojE-yoyC-yojF-bshB2 (minor transcript) PubMed
  • yoyC-yojF-bshB2 (major transcript) PubMed

• Expression browser: yoyC PubMed

• Sigma factor:
  • yojE: SigA PubMed
  • yoyC: SigA PubMed

• Regulation:
  • yoyC: induced by diamide stess (thiol depletion) (Spx) PubMed

• Regulatory mechanism:
  • Spx: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Operon and expression

Ahmed Gaballa, Haike Antelmann, Chris J Hamilton, John D Helmann
Regulation of Bacillus subtilis bacillithiol biosynthesis operons by Spx.
Microbiology (Reading): 2013, 159(Pt 10);2025-2035
[PubMed:23894131] [WorldCat.org] [DOI] (I p)

Ahmed Gaballa, Gerald L Newton, Haike Antelmann, Derek Parsonage, Heather Upton, Mamta Rawat, Al Claiborne, Robert C Fahey, John D Helmann
Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli.
Proc Natl Acad Sci U S A: 2010, 107(14);6482-6
[PubMed:20308541] [WorldCat.org] [DOI] (I p)