Difference between revisions of "FtsE"
| Line 99: | Line 99: | ||
=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' | + | * '''Structure:''' http://www.rcsb.org/pdb/explore/explore.do?pdbId=3TIF 3TIF (ATP-binding protein from ''Methanococcus jannaschii'') {{PubMed|22158619}} |
* '''UniProt:''' [http://www.uniprot.org/uniprot/O34814 O34814] | * '''UniProt:''' [http://www.uniprot.org/uniprot/O34814 O34814] | ||
| Line 144: | Line 144: | ||
=References= | =References= | ||
| − | <pubmed>10092453,18573177,,14651647, </pubmed> | + | <pubmed>10092453,18573177, 22158619,14651647, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 12:27, 16 July 2013
- Description: ABC transporter (ATP-binding protein) (FtsE-FtsX), required for CwlO activity and for proper activation of Spo0A and initiation of sporulation
| Gene name | ftsE |
| Synonyms | |
| Essential | no |
| Product | ABC transporter (ATP-binding protein) |
| Function | control of cell wall synthesis |
| Gene expression levels in SubtiExpress: ftsE | |
| Interactions involving this protein in SubtInteract: FtsE | |
| MW, pI | 25 kDa, 8.419 |
| Gene length, protein length | 684 bp, 228 aa |
| Immediate neighbours | ftsX, cccB |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
ABC transporters, cell wall synthesis, phosphorelay, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU35260
Phenotypes of a mutant
- a ftsE mutation is synthetically lethal with a lytE mutation (due to a lack of autolysin activity) PubMed
- shorter, fatter cells PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: membrane associated (via FtsX) PubMed
Database entries
- Structure: http://www.rcsb.org/pdb/explore/explore.do?pdbId=3TIF 3TIF (ATP-binding protein from Methanococcus jannaschii) PubMed
- UniProt: O34814
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Maria E Zoghbi, Kerry L Fuson, Roger B Sutton, Guillermo A Altenberg
Kinetics of the association/dissociation cycle of an ATP-binding cassette nucleotide-binding domain.
J Biol Chem: 2012, 287(6);4157-64
[PubMed:22158619]
[WorldCat.org]
[DOI]
(I p)
Sharon Garti-Levi, Ronen Hazan, James Kain, Masaya Fujita, Sigal Ben-Yehuda
The FtsEX ABC transporter directs cellular differentiation in Bacillus subtilis.
Mol Microbiol: 2008, 69(4);1018-28
[PubMed:18573177]
[WorldCat.org]
[DOI]
(I p)
Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647]
[WorldCat.org]
[DOI]
(P p)
Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453]
[WorldCat.org]
[DOI]
(P p)
