YrhH

• Description: similar to methyltransferase
  
  

Gene name	yrhH
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: yrhH
MW, pI	20 kDa, 10.159
Gene length, protein length	540 bp, 180 aa
Immediate neighbours	fatR, yrzI
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed 500px

Categories containing this gene/protein

cell envelope stress proteins (controlled by SigM, V, W, X, Y), poorly characterized/ putative enzymes

This gene is a member of the following regulons

SigM regulon, SigW regulon, SigX regulon

The gene

Basic information

• Locus tag: BSU27180

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: methyltransferase superfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O05400

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:
  • yrhH PubMed
  • yrhH-fatR-yrhJ PubMed

• Expression browser: yrhH PubMed

• Sigma factor: SigW PubMed, SigM PubMed, SigX PubMed

• Regulation:
  • Expressed under stress conditions (SigW, SigX) PubMed
  • expression is reduced in a SigV mutant PubMed

• Regulatory mechanism:

• Additional information:
  • the mRNA is substantially stabilized upon depletion of RNase Y PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Veronica Guariglia-Oropeza, John D Helmann
Bacillus subtilis σ(V) confers lysozyme resistance by activation of two cell wall modification pathways, peptidoglycan O-acetylation and D-alanylation of teichoic acids.
J Bacteriol: 2011, 193(22);6223-32
[PubMed:21926231] [WorldCat.org] [DOI] (I p)

Martin Lehnik-Habrink, Marc Schaffer, Ulrike Mäder, Christine Diethmaier, Christina Herzberg, Jörg Stülke
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y.
Mol Microbiol: 2011, 81(6);1459-73
[PubMed:21815947] [WorldCat.org] [DOI] (I p)

Warawan Eiamphungporn, John D Helmann
The Bacillus subtilis sigma(M) regulon and its contribution to cell envelope stress responses.
Mol Microbiol: 2008, 67(4);830-48
[PubMed:18179421] [WorldCat.org] [DOI] (P p)

X Huang, K L Fredrick, J D Helmann
Promoter recognition by Bacillus subtilis sigmaW: autoregulation and partial overlap with the sigmaX regulon.
J Bacteriol: 1998, 180(15);3765-70
[PubMed:9683469] [WorldCat.org] [DOI] (P p)