Difference between revisions of "YbxA"
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || ECF [[transporter | + | |style="background:#ABCDEF;" align="center"| '''Product''' || ECF [[transporters|transporter]] (ATP-binding protein) |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || uptake of micronutrients | |style="background:#ABCDEF;" align="center"|'''Function''' || uptake of micronutrients | ||
| Line 40: | Line 40: | ||
= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| − | {{SubtiWiki category|[[ | + | {{SubtiWiki category|[[transporters/ other]]}}, |
{{SubtiWiki category|[[membrane proteins]]}} | {{SubtiWiki category|[[membrane proteins]]}} | ||
| Line 71: | Line 71: | ||
* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
| − | * '''Protein family:''' | + | * '''Protein family:''' EcfA transporter |
* '''Paralogous protein(s):''' | * '''Paralogous protein(s):''' | ||
| Line 95: | Line 95: | ||
* '''Structure:''' | * '''Structure:''' | ||
| + | ** [http://www.rcsb.org/pdb/explore/explore.do?structureId=4huq 4HUQ] (EcfA1-EcfA2-EcfT-FolT complex of ''Lactobacillus brevis''), {{PubMed|23584589}} | ||
* '''UniProt:''' [http://www.uniprot.org/uniprot/P40735 P40735] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P40735 P40735] | ||
Revision as of 19:04, 12 July 2013
- Description: ATP-binding A1 component of ECT transporters
| Gene name | ybxA |
| Synonyms | ybaD, ecfA1 |
| Essential | no |
| Product | ECF transporter (ATP-binding protein) |
| Function | uptake of micronutrients |
| Gene expression levels in SubtiExpress: ybxA | |
| Interactions involving this protein in SubtInteract: YbxA | |
| MW, pI | 31 kDa, 4.766 |
| Gene length, protein length | 843 bp, 281 aa |
| Immediate neighbours | rplQ, ybaE |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
transporters/ other, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU01450
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: EcfA transporter
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: membrane associated (via YbaF) PubMed
Database entries
- UniProt: P40735
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Thomas Eitinger, Dmitry A Rodionov, Mathias Grote, Erwin Schneider
Canonical and ECF-type ATP-binding cassette importers in prokaryotes: diversity in modular organization and cellular functions.
FEMS Microbiol Rev: 2011, 35(1);3-67
[PubMed:20497229]
[WorldCat.org]
[DOI]
(I p)
Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453]
[WorldCat.org]
[DOI]
(P p)
Original publications
Ke Xu, Minhua Zhang, Qin Zhao, Fang Yu, Hui Guo, Chengyuan Wang, Fangyuan He, Jianping Ding, Peng Zhang
Crystal structure of a folate energy-coupling factor transporter from Lactobacillus brevis.
Nature: 2013, 497(7448);268-71
[PubMed:23584589]
[WorldCat.org]
[DOI]
(I p)
Josy ter Beek, Ria H Duurkens, Guus B Erkens, Dirk Jan Slotboom
Quaternary structure and functional unit of energy coupling factor (ECF)-type transporters.
J Biol Chem: 2011, 286(7);5471-5
[PubMed:21135102]
[WorldCat.org]
[DOI]
(I p)
