Difference between revisions of "HutP"

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(Original publications)
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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
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** HutP binds its RNA target to cause antitermination in the presence of histidine {{PubMed|23748184}}
  
 
* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=hutP_4041483_4041938_1 hutP] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=hutP_4041483_4041938_1 hutP] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigA]] {{PubMed|8071225}}  
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* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|8071225}}  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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==Original publications==
 
==Original publications==
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'''Additional publications:''' {{PubMed|23748184}}
 
<pubmed>12903241,8682780, 8071225 10217782 18083814 22900538 23748184 </pubmed>
 
<pubmed>12903241,8682780, 8071225 10217782 18083814 22900538 23748184 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 08:32, 12 June 2013

  • Description: transcriptional antiterminator of the hut operon

Gene name hutP
Synonyms hutP1
Essential no
Product transcriptional antiterminator
Function regulation of histidine utilization
Gene expression levels in SubtiExpress: hutP
Metabolic function and regulation of this protein in SubtiPathways:
His
MW, pI 16 kDa, 6.057
Gene length, protein length 453 bp, 151 aa
Immediate neighbours yxzL, hutH
Sequences Protein DNA DNA_with_flanks
Genetic context
HutP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
500px















Categories containing this gene/protein

utilization of amino acids, transcription factors and their control, RNA binding regulators

This gene is a member of the following regulons

CcpA regulon, CodY regulon

The HutP regulon: hutH-hutU-hutI-hutG-hutM

The gene

Basic information

  • Locus tag: BSU39340

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: hutP family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
    • HutP binds its RNA target to cause antitermination in the presence of histidine PubMed

Database entries

  • Structure: 3BOY (complex bound to the hut mRNA), 1WPT
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by glucose (CcpA) PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews


Original publications

Additional publications: PubMed