Difference between revisions of "RNA polymerase"
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=='''The enzyme responsible for [[transcription]]'''== | =='''The enzyme responsible for [[transcription]]'''== | ||
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===Other interaction partners=== | ===Other interaction partners=== | ||
* [[NusA]]: essential elongation factor | * [[NusA]]: essential elongation factor | ||
| − | * [[GreA]]: | + | * [[GreA]]: resolves promoter proximal pausing of RNA polymerase {{PubMed|21515770}} |
* [[CshA]]: [[DEAD-box RNA helicases|DEAD-box RNA helicase]] {{PubMed|21710567}} | * [[CshA]]: [[DEAD-box RNA helicases|DEAD-box RNA helicase]] {{PubMed|21710567}} | ||
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* [[MgsR]]: transcription regulator orthologous to [[Spx]], interacts with [[RpoA]] | * [[MgsR]]: transcription regulator orthologous to [[Spx]], interacts with [[RpoA]] | ||
* [[Btr]]: transcription activator {{PubMed|22210890}} | * [[Btr]]: transcription activator {{PubMed|22210890}} | ||
| − | + | * [[YlyA]]: modulates [[SigG]]-dependent transcription {{PubMed|23678950}} | |
* '''Additional interaction partners of the RNA polymerase (no specific subunit specified)''' | * '''Additional interaction partners of the RNA polymerase (no specific subunit specified)''' | ||
Revision as of 17:21, 24 May 2013
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Contents
The enzyme responsible for transcription
Components of the RNA polymerase
Core subunits
Sigma factors
- In addition to the housekeeping sigma factor, SigA, there are several other sigma factors with different promoter recognition specifiity that are active under specific conditions (such as stress or sporulation)
Small accessory subunits
Other interaction partners
- NusA: essential elongation factor
- GreA: resolves promoter proximal pausing of RNA polymerase PubMed
- CshA: DEAD-box RNA helicase PubMed
Temporary interaction partners
- Spx: transcription regulator, interacts with RpoA
- MgsR: transcription regulator orthologous to Spx, interacts with RpoA
- Btr: transcription activator PubMed
- YlyA: modulates SigG-dependent transcription PubMed
- Additional interaction partners of the RNA polymerase (no specific subunit specified)
Back to protein-protein interactions
References
Reviews
The structure of RNA polymerase
Elecia B Johnston, Peter J Lewis, Renate Griffith
The interaction of Bacillus subtilis sigmaA with RNA polymerase.
Protein Sci: 2009, 18(11);2287-97
[PubMed:19735077]
[WorldCat.org]
[DOI]
(I p)
Sergei Borukhov, Evgeny Nudler
RNA polymerase holoenzyme: structure, function and biological implications.
Curr Opin Microbiol: 2003, 6(2);93-100
[PubMed:12732296]
[WorldCat.org]
[DOI]
(P p)
Katsuhiko S Murakami, Seth A Darst
Bacterial RNA polymerases: the wholo story.
Curr Opin Struct Biol: 2003, 13(1);31-9
[PubMed:12581657]
[WorldCat.org]
[DOI]
(P p)
S A Darst
Bacterial RNA polymerase.
Curr Opin Struct Biol: 2001, 11(2);155-62
[PubMed:11297923]
[WorldCat.org]
[DOI]
(P p)
Important original publications
