Difference between revisions of "AdeR"

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Revision as of 14:28, 16 May 2013

  • Description: transcription activator (PucR family) for ald gene expression

Gene name adeR
Synonyms yukF
Essential no
Product transcription activator (PucR family)
Function control of ald expression
MW, pI 50 kDa, 8.147
Gene length, protein length 1302 bp, 434 aa
Immediate neighbours yukE, ald
Sequences Protein DNA DNA_with_flanks
Genetic context
YukF context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YukF expression.png















Categories containing this gene/protein

transcription factors and their control, utilization of amino acids

This gene is a member of the following regulons

The AdeR regulon

The gene

Basic information

  • Locus tag: BSU31920

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: transcription activation of ald gene expression in the presence of alanine PubMed
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylated on Ser-395 PubMed
  • Cofactor(s):
  • Effectors of protein activity: L-alanine PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • constitutively expressed PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Boumediene Soufi, Chanchal Kumar, Florian Gnad, Matthias Mann, Ivan Mijakovic, Boris Macek
Stable isotope labeling by amino acids in cell culture (SILAC) applied to quantitative proteomics of Bacillus subtilis.
J Proteome Res: 2010, 9(7);3638-46
[PubMed:20509597] [WorldCat.org] [DOI] (I p)

K J Siranosian, K Ireton, A D Grossman
Alanine dehydrogenase (ald) is required for normal sporulation in Bacillus subtilis.
J Bacteriol: 1993, 175(21);6789-96
[PubMed:8226620] [WorldCat.org] [DOI] (P p)