Difference between revisions of "GltR"

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Revision as of 14:01, 16 May 2013

Gene name gltR
Synonyms yrdL
Essential no
Product transcriptional regulator (LysR family)
Function unknown
Gene expression levels in SubtiExpress: gltR
MW, pI 32 kDa, 6.653
Gene length, protein length 888 bp, 296 aa
Immediate neighbours yrdN, yrdK
Sequences Protein DNA DNA_with_flanks
Genetic context
GltR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
GltR expression.png
























Categories containing this gene/protein

transcription factors and their control

This gene is a member of the following regulons

GltR regulon

The GltR regulon:

The gene

Basic information

  • Locus tag: BSU26670

Phenotypes of a mutant

The function of this protein is unknown. However, certain mutant forms are able to activate expression of the gltA-gltB operon (and thus to replace the cognate activator protein GltC)

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

The function of this protein is unknown. However, certain mutant forms are able to activate expression of the gltA-gltB operon (and thus to replace the cognate activator protein GltC)

Expression and regulation

  • Operon: gltR (according to DBTBS)
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant: GP345 (erm), available in the Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Linc Sonenshein, Tufts University, Boston, MA, USA Homepage

Your additional remarks

References

B R Belitsky, A L Sonenshein
Altered transcription activation specificity of a mutant form of Bacillus subtilis GltR, a LysR family member.
J Bacteriol: 1997, 179(4);1035-43
[PubMed:9023181] [WorldCat.org] [DOI] (P p)