Difference between revisions of "YneA"

From SubtiWiki
Jump to: navigation, search
Line 27: Line 27:
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
|-
 
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yneA_1918406_1918723_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:yneA_expression.png|500px]]
+
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yneA_1918406_1918723_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:yneA_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU17860]]
 
|-
 
|-
 
|}
 
|}

Revision as of 13:28, 16 May 2013

  • Description: inhibits cell division during SOS response

Gene name yneA
Synonyms
Essential no
Product cell division control protein
Function inhibits cell division during SOS response
Gene expression levels in SubtiExpress: yneA
MW, pI 11 kDa, 4.613
Gene length, protein length 315 bp, 105 aa
Immediate neighbours lexA, yneB
Sequences Protein DNA DNA_with_flanks
Genetic context
YneA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YneA expression.png















Categories containing this gene/protein

cell division

This gene is a member of the following regulons

LexA regulon

The gene

Basic information

  • Locus tag: BSU17860

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: yneA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
    • LysM peptidoglycan binding domain PubMed
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:
    • YneA is rapidly degraded by extracellular proteases PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Allison H Mo, William F Burkholder
YneA, an SOS-induced inhibitor of cell division in Bacillus subtilis, is regulated posttranslationally and requires the transmembrane region for activity.
J Bacteriol: 2010, 192(12);3159-73
[PubMed:20400548] [WorldCat.org] [DOI] (I p)

Nora Au, Elke Kuester-Schoeck, Veena Mandava, Laura E Bothwell, Susan P Canny, Karen Chachu, Sierra A Colavito, Shakierah N Fuller, Eli S Groban, Laura A Hensley, Theresa C O'Brien, Amish Shah, Jessica T Tierney, Louise L Tomm, Thomas M O'Gara, Alexi I Goranov, Alan D Grossman, Charles M Lovett
Genetic composition of the Bacillus subtilis SOS system.
J Bacteriol: 2005, 187(22);7655-66
[PubMed:16267290] [WorldCat.org] [DOI] (P p)

Yoshikazu Kawai, Shigeki Moriya, Naotake Ogasawara
Identification of a protein, YneA, responsible for cell division suppression during the SOS response in Bacillus subtilis.
Mol Microbiol: 2003, 47(4);1113-22
[PubMed:12581363] [WorldCat.org] [DOI] (P p)