Difference between revisions of "SecE"
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Revision as of 12:21, 16 May 2013
- Description: preprotein translocase subunit
| Gene name | secE |
| Synonyms | |
| Essential | yes PubMed |
| Product | preprotein translocase subunit |
| Function | protein secretion |
| Gene expression levels in SubtiExpress: secE | |
| Interactions involving this protein in SubtInteract: SecE | |
| Metabolic function and regulation of this protein in SubtiPathways: Protein secretion | |
| MW, pI | 6 kDa, 10.47 |
| Gene length, protein length | 177 bp, 59 aa |
| Immediate neighbours | rpmGB, nusG |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
protein secretion, essential genes, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU01000
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: secE/SEC61-gamma family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: transmembrane protein with a single TM domain
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- UniProt: Q06799
- KEGG entry: [2]
- E.C. number:
Additional information
B. subtilis secE complements the secretion phenotype of a cold sensitive E. coli secE mutant.
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Jochen Zimmer, Yunsun Nam, Tom A Rapoport
Structure of a complex of the ATPase SecA and the protein-translocation channel.
Nature: 2008, 455(7215);936-43
[PubMed:18923516]
[WorldCat.org]
[DOI]
(I p)
S M Jeong, H Yoshikawa, H Takahashi
Isolation and characterization of the secE homologue gene of Bacillus subtilis.
Mol Microbiol: 1993, 10(1);133-42
[PubMed:7968510]
[WorldCat.org]
[DOI]
(P p)
