Difference between revisions of "ComQ"
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[comX]]'', ''[[degQ]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[comX]]'', ''[[degQ]]'' | ||
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| − | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU31710 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU31710 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU31710 | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU31710 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU31710 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU31710 DNA_with_flanks] |
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Revision as of 11:09, 14 May 2013
- Description: prenylation of ComX, regulator of late competence operon (comG) and surfactin expression (srfA)
| Gene name | comQ |
| Synonyms | |
| Essential | no |
| Product | prenyltransferase |
| Function | regulation of quorum sensing |
| Gene expression levels in SubtiExpress: comQ | |
| Interactions involving this protein in SubtInteract: ComQ | |
| MW, pI | 34 kDa, 4.893 |
| Gene length, protein length | 897 bp, 299 aa |
| Immediate neighbours | comX, degQ |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
genetic competence, quorum sensing, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU31710
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P33690
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Fumitada Tsuji, Ayako Ishihara, Aya Nakagawa, Masahiro Okada, Shigeyuki Kitamura, Kyoko Kanamaru, Yuichi Masuda, Kazuma Murakami, Kazuhiro Irie, Youji Sakagami
Lack of the consensus sequence necessary for tryptophan prenylation in the ComX pheromone precursor.
Biosci Biotechnol Biochem: 2012, 76(8);1492-6
[PubMed:22878193]
[WorldCat.org]
[DOI]
(I p)
Daniel López, Hera Vlamakis, Richard Losick, Roberto Kolter
Paracrine signaling in a bacterium.
Genes Dev: 2009, 23(14);1631-8
[PubMed:19605685]
[WorldCat.org]
[DOI]
(I p)
Polonca Stefanic, Ines Mandic-Mulec
Social interactions and distribution of Bacillus subtilis pherotypes at microscale.
J Bacteriol: 2009, 191(6);1756-64
[PubMed:19114482]
[WorldCat.org]
[DOI]
(I p)
Mireille Ansaldi, Darja Marolt, Tina Stebe, Ines Mandic-Mulec, David Dubnau
Specific activation of the Bacillus quorum-sensing systems by isoprenylated pheromone variants.
Mol Microbiol: 2002, 44(6);1561-73
[PubMed:12067344]
[WorldCat.org]
[DOI]
(P p)
P Tortosa, L Logsdon, B Kraigher, Y Itoh, I Mandic-Mulec, D Dubnau
Specificity and genetic polymorphism of the Bacillus competence quorum-sensing system.
J Bacteriol: 2001, 183(2);451-60
[PubMed:11133937]
[WorldCat.org]
[DOI]
(P p)
Y Weinrauch, T Msadek, F Kunst, D Dubnau
Sequence and properties of comQ, a new competence regulatory gene of Bacillus subtilis.
J Bacteriol: 1991, 173(18);5685-93
[PubMed:1715859]
[WorldCat.org]
[DOI]
(P p)
