Difference between revisions of "Tpx"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytxK]]'', ''[[ytfJ]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytxK]]'', ''[[ytfJ]]''
 
|-
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU29490 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU29490 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU29490 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU29490 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU29490 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU29490 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:tpx_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:tpx_context.gif]]

Revision as of 11:00, 14 May 2013

  • Description: probable thiol peroxidase

Gene name tpx
Synonyms ytgI
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: tpx
MW, pI 18 kDa, 4.698
Gene length, protein length 501 bp, 167 aa
Immediate neighbours ytxK, ytfJ
Sequences Protein DNA DNA_with_flanks
Genetic context
Tpx context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Tpx expression.png
























Categories containing this gene/protein

resistance against oxidative and electrophile stress

This gene is a member of the following regulons

Spx regulon

The gene

Basic information

  • Locus tag: BSU29490

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: Tpx subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jie Lu, Fan Yang, You Li, Bin Xia, Changwen Jin
1H, 13C, and 15N resonance assignments of the reduced and oxidized forms of Bacillus subtilis thiol peroxidase.
Biomol NMR Assign: 2008, 2(2);183-6
[PubMed:19636900] [WorldCat.org] [DOI] (I p)

Shunji Nakano, Michiko M Nakano, Ying Zhang, Montira Leelakriangsak, Peter Zuber
A regulatory protein that interferes with activator-stimulated transcription in bacteria.
Proc Natl Acad Sci U S A: 2003, 100(7);4233-8
[PubMed:12642660] [WorldCat.org] [DOI] (P p)

Alia Lapidus, Nathalie Galleron, Alexei Sorokin, S Dusko Ehrlich
Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region.
Microbiology (Reading): 1997, 143 ( Pt 11);3431-3441
[PubMed:9387221] [WorldCat.org] [DOI] (P p)