YodB

• Description: MarR/DUF24 family transcription repressor of azoR1, catD-catE and yodC expression
  
  

Gene name	yodB
Synonyms
Essential	no
Product	MarR/DUF24 family transcription repressor
Function	regulation of quinone and diamide detoxification
Gene expression levels in SubtiExpress: yodB
MW, pI	12 kDa, 4.737
Gene length, protein length	336 bp, 112 aa
Immediate neighbours	yodA, yodC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control, resistance against oxidative and electrophile stress

This gene is a member of the following regulons

YodB regulon

The YodB regulon:

• azoR1, catD-catE, yodB, yodC

The gene

Basic information

• Locus tag: BSU19540

Phenotypes of a mutant

• increased resistance to catechol, quinones and diamide PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: MarR/DUF24 family

• Paralogous protein(s): CatR

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: redox-controlled by intersubunit disulfide formation of Cys6 and Cys101' in response to quinones and diamide

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O34844

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yodB PubMed

• Sigma factor:

• Regulation:
  • subject to autorepression PubMed

• Regulatory mechanism:
  • YodB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Haike Antelmann,University of Greifswald, Germany

References

Reviews

Antelmann H, Helmann JD.
Thiol-based redox switches and gene regulation.
Antioxid Redox Signal. 2011,14:1049-63.
PubMed