Difference between revisions of "SodF"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sqhC]]'', ''[[yocR]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sqhC]]'', ''[[yocR]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU19330 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU19330 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU19330 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU19330 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU19330 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU19330 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:sodF_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:sodF_context.gif]]

Revision as of 10:25, 14 May 2013

  • Description: superoxide dismutase

Gene name sodF
Synonyms
Essential no
Product superoxide dismutase
Function detoxification of oxygen radicals
Gene expression levels in SubtiExpress: sodF
MW, pI 33 kDa, 6.17
Gene length, protein length 843 bp, 281 aa
Immediate neighbours sqhC, yocR
Sequences Protein DNA DNA_with_flanks
Genetic context
SodF context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SodF expression.png
























Categories containing this gene/protein

sporulation proteins, resistance against oxidative and electrophile stress, membrane proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

  • Locus tag: BSU19330

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2 superoxide + 2 H+ = O2 + H2O2 (according to Swiss-Prot)
  • Protein family: terpene cyclase/mutase family (according to Swiss-Prot)
  • Paralogous protein(s): SodA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s): contains an iron-sulfur cluster
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: expressed during sporulation in the mother cell PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

T Bosak, R M Losick, A Pearson
A polycyclic terpenoid that alleviates oxidative stress.
Proc Natl Acad Sci U S A: 2008, 105(18);6725-9
[PubMed:18436644] [WorldCat.org] [DOI] (I p)